A method to construct the dynamic landscape of a bio-membrane with experiment and simulation
The authors present a strategy to construct dynamic biomolecular landscapes. Here, they derive a quantitative description of the distribution timescales and amplitudes of reorientational motion of POPC membranes from the combination of NMR relaxation data and frame analysis of MD simulations.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-27417-y |
| _version_ | 1828138420603453440 |
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| author | Albert A. Smith Alexander Vogel Oskar Engberg Peter W. Hildebrand Daniel Huster |
| author_facet | Albert A. Smith Alexander Vogel Oskar Engberg Peter W. Hildebrand Daniel Huster |
| author_sort | Albert A. Smith |
| collection | DOAJ |
| description | The authors present a strategy to construct dynamic biomolecular landscapes. Here, they derive a quantitative description of the distribution timescales and amplitudes of reorientational motion of POPC membranes from the combination of NMR relaxation data and frame analysis of MD simulations. |
| first_indexed | 2024-04-11T18:36:33Z |
| format | Article |
| id | doaj.art-89871a20a2734823abf1f8d54718c7d3 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T18:36:33Z |
| publishDate | 2022-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-89871a20a2734823abf1f8d54718c7d32022-12-22T04:09:15ZengNature PortfolioNature Communications2041-17232022-01-0113111310.1038/s41467-021-27417-yA method to construct the dynamic landscape of a bio-membrane with experiment and simulationAlbert A. Smith0Alexander Vogel1Oskar Engberg2Peter W. Hildebrand3Daniel Huster4Institute for Medical Physics and Biophysics, Leipzig UniversityInstitute for Medical Physics and Biophysics, Leipzig UniversityInstitute for Medical Physics and Biophysics, Leipzig UniversityInstitute for Medical Physics and Biophysics, Leipzig UniversityInstitute for Medical Physics and Biophysics, Leipzig UniversityThe authors present a strategy to construct dynamic biomolecular landscapes. Here, they derive a quantitative description of the distribution timescales and amplitudes of reorientational motion of POPC membranes from the combination of NMR relaxation data and frame analysis of MD simulations.https://doi.org/10.1038/s41467-021-27417-y |
| spellingShingle | Albert A. Smith Alexander Vogel Oskar Engberg Peter W. Hildebrand Daniel Huster A method to construct the dynamic landscape of a bio-membrane with experiment and simulation Nature Communications |
| title | A method to construct the dynamic landscape of a bio-membrane with experiment and simulation |
| title_full | A method to construct the dynamic landscape of a bio-membrane with experiment and simulation |
| title_fullStr | A method to construct the dynamic landscape of a bio-membrane with experiment and simulation |
| title_full_unstemmed | A method to construct the dynamic landscape of a bio-membrane with experiment and simulation |
| title_short | A method to construct the dynamic landscape of a bio-membrane with experiment and simulation |
| title_sort | method to construct the dynamic landscape of a bio membrane with experiment and simulation |
| url | https://doi.org/10.1038/s41467-021-27417-y |
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