Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines.

To gain insight into the role of genomic alterations in breast cancer progression, we conducted a comprehensive genetic characterization of a series of four cell lines derived from MCF10A. MCF10A is an immortalized mammary epithelial cell line (MEC); MCF10AT is a premalignant cell line generated fro...

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Bibliographic Details
Main Authors: Mitsutaka Kadota, Howard H Yang, Bianca Gomez, Misako Sato, Robert J Clifford, Daoud Meerzaman, Barbara K Dunn, Lalage M Wakefield, Maxwell P Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2821407?pdf=render