Mutation in Spike Protein Cleavage Site and Pathogenesis of Feline Coronavirus

Mutation in Spike Protein Cleavage Site and Pathogenesis of Feline Coronavirus

Feline coronaviruses (FCoV) exist as 2 biotypes: feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV). FECV causes subclinical infections; FIPV causes feline infectious peritonitis (FIP), a systemic and fatal disease. It is thought that mutations in FECV enable infection...

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Bibliographic Details
Main Authors: Beth N. Licitra, Jean K. Millet, Andrew D. Regan, Brian S. Hamilton, Vera D. Rinaldi, Gerald E. Duhamel, Gary R. Whittaker
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2013-07-01
Series:Emerging Infectious Diseases
Subjects:
Macrophage
pathology
protease
protein processing
feline coronavirus, viruses, conserved furin cleavage motif
feline coronavirus
Online Access:https://wwwnc.cdc.gov/eid/article/19/7/12-1094_article

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