Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?

Objective: To assess the efficiency of dual energy contrast enhanced mammography in the assessment of the indeterminate breast lesions (BIRADS 3 and BIRADS 4). Materials and methods: 34 female having 39 indeterminate breast lesions (BIRADS 3 and BIRADS 4) by digital mammography were further examined...

Full description

Bibliographic Details
Main Authors: Samira Saraya, Lamia Adel, Asmaa Mahmoud
Format: Article
Language:English
Published: SpringerOpen 2017-06-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0378603X17300529
_version_ 1819076871120224256
author Samira Saraya
Lamia Adel
Asmaa Mahmoud
author_facet Samira Saraya
Lamia Adel
Asmaa Mahmoud
author_sort Samira Saraya
collection DOAJ
description Objective: To assess the efficiency of dual energy contrast enhanced mammography in the assessment of the indeterminate breast lesions (BIRADS 3 and BIRADS 4). Materials and methods: 34 female having 39 indeterminate breast lesions (BIRADS 3 and BIRADS 4) by digital mammography were further examined by dual energy contrast enhanced mammography. Two images were acquired at low and high energy in MLO view after 2 min and in CC view at 4 min post iodinated contrast injection (1.5 ml/kg with flow of 4 ml/s). Images were processed to obtain subtracted images to enhance the areas of the contrast uptake. Results: Results from pathology were detected for all cases. Contrast enhanced digital mammography showed specificity, sensitivity, PPV, NPV, FDR, FPR and accuracy of 93.75%, 91.3%, 88.2%, 95.4%, 11.7%, 8.6% and 92.3% respectively compared to full field digital mammography which were 68.75%, 69.5%, 61.1%, 76.1%, 38.8%, 30% and 69.2% respectively. Conclusion: Contrast-enhanced digital mammography is a useful tool to be used for breast cancer detection especially in indeterminate lesions (BIRADS 3 and 4).
first_indexed 2024-12-21T18:48:11Z
format Article
id doaj.art-898f398b23fe4d83959c2e4efe31a3cd
institution Directory Open Access Journal
issn 0378-603X
language English
last_indexed 2024-12-21T18:48:11Z
publishDate 2017-06-01
publisher SpringerOpen
record_format Article
series The Egyptian Journal of Radiology and Nuclear Medicine
spelling doaj.art-898f398b23fe4d83959c2e4efe31a3cd2022-12-21T18:53:49ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2017-06-0148254755210.1016/j.ejrnm.2017.03.006Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?Samira SarayaLamia AdelAsmaa MahmoudObjective: To assess the efficiency of dual energy contrast enhanced mammography in the assessment of the indeterminate breast lesions (BIRADS 3 and BIRADS 4). Materials and methods: 34 female having 39 indeterminate breast lesions (BIRADS 3 and BIRADS 4) by digital mammography were further examined by dual energy contrast enhanced mammography. Two images were acquired at low and high energy in MLO view after 2 min and in CC view at 4 min post iodinated contrast injection (1.5 ml/kg with flow of 4 ml/s). Images were processed to obtain subtracted images to enhance the areas of the contrast uptake. Results: Results from pathology were detected for all cases. Contrast enhanced digital mammography showed specificity, sensitivity, PPV, NPV, FDR, FPR and accuracy of 93.75%, 91.3%, 88.2%, 95.4%, 11.7%, 8.6% and 92.3% respectively compared to full field digital mammography which were 68.75%, 69.5%, 61.1%, 76.1%, 38.8%, 30% and 69.2% respectively. Conclusion: Contrast-enhanced digital mammography is a useful tool to be used for breast cancer detection especially in indeterminate lesions (BIRADS 3 and 4).http://www.sciencedirect.com/science/article/pii/S0378603X17300529Breast cancerFull field digital mammographyContrast enhanced digital mammographyBIRADS 3 and 4
spellingShingle Samira Saraya
Lamia Adel
Asmaa Mahmoud
Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?
The Egyptian Journal of Radiology and Nuclear Medicine
Breast cancer
Full field digital mammography
Contrast enhanced digital mammography
BIRADS 3 and 4
title Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?
title_full Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?
title_fullStr Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?
title_full_unstemmed Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?
title_short Indeterminate breast lesions: Can contrast enhanced digital mammography change our decisions?
title_sort indeterminate breast lesions can contrast enhanced digital mammography change our decisions
topic Breast cancer
Full field digital mammography
Contrast enhanced digital mammography
BIRADS 3 and 4
url http://www.sciencedirect.com/science/article/pii/S0378603X17300529
work_keys_str_mv AT samirasaraya indeterminatebreastlesionscancontrastenhanceddigitalmammographychangeourdecisions
AT lamiaadel indeterminatebreastlesionscancontrastenhanceddigitalmammographychangeourdecisions
AT asmaamahmoud indeterminatebreastlesionscancontrastenhanceddigitalmammographychangeourdecisions