Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum
The seven most early diverging lineages of the 18 phyla of fungi are the non-terrestrial fungi, which reproduce through motile flagellated zoospores. There are genes/proteins that are present only in organisms with flagellum or cilium. It was suggested that TPPP-like proteins (proteins containing at...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-03-01
|
| Series: | Journal of Fungi |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2309-608X/9/3/376 |
| _version_ | 1797610809328664576 |
|---|---|
| author | Ferenc Orosz |
| author_facet | Ferenc Orosz |
| author_sort | Ferenc Orosz |
| collection | DOAJ |
| description | The seven most early diverging lineages of the 18 phyla of fungi are the non-terrestrial fungi, which reproduce through motile flagellated zoospores. There are genes/proteins that are present only in organisms with flagellum or cilium. It was suggested that TPPP-like proteins (proteins containing at least one complete or partial p25alpha domain) are among them, and a correlation between the incidence of the p25alpha domain and the eukaryotic flagellum was hypothesized. Of the seven phyla of flagellated fungi, six have been known to contain TPPP-like proteins. Aphelidiomycota, one of the early-branching phyla, has some species (e.g., <i>Paraphelidium tribonematis</i>) that retain the flagellum, whereas the <i>Amoeboaphelidium</i> genus has lost the flagellum. The first two Aphelidiomycota genomes (<i>Amoeboaphelidium protococcorum</i> and <i>Amoeboaphelidium occidentale</i>) were sequenced and published last year. A BLASTP search revealed that <i>A. occidentale</i> does not have a TPPP, but <i>A. protococcorum</i>, which possesses pseudocilium, does have a TPPP. This TPPP is the ‘long-type’ which occurs mostly in animals as well as other Opisthokonta. <i>P. tribonematis</i> has a ‘fungal-type’ TPPP, which is found only in some flagellated fungi. These data on Aphelidiomycota TPPP proteins strengthen the correlation between the incidence of p25alpha domain-containing proteins and that of the eukaryotic flagellum/cilium. |
| first_indexed | 2024-03-11T06:20:14Z |
| format | Article |
| id | doaj.art-8990fd573d1844fdbf2b02fc3f3a6c0e |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-11T06:20:14Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-8990fd573d1844fdbf2b02fc3f3a6c0e2023-11-17T12:00:42ZengMDPI AGJournal of Fungi2309-608X2023-03-019337610.3390/jof9030376Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic FlagellumFerenc Orosz0Research Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, HungaryThe seven most early diverging lineages of the 18 phyla of fungi are the non-terrestrial fungi, which reproduce through motile flagellated zoospores. There are genes/proteins that are present only in organisms with flagellum or cilium. It was suggested that TPPP-like proteins (proteins containing at least one complete or partial p25alpha domain) are among them, and a correlation between the incidence of the p25alpha domain and the eukaryotic flagellum was hypothesized. Of the seven phyla of flagellated fungi, six have been known to contain TPPP-like proteins. Aphelidiomycota, one of the early-branching phyla, has some species (e.g., <i>Paraphelidium tribonematis</i>) that retain the flagellum, whereas the <i>Amoeboaphelidium</i> genus has lost the flagellum. The first two Aphelidiomycota genomes (<i>Amoeboaphelidium protococcorum</i> and <i>Amoeboaphelidium occidentale</i>) were sequenced and published last year. A BLASTP search revealed that <i>A. occidentale</i> does not have a TPPP, but <i>A. protococcorum</i>, which possesses pseudocilium, does have a TPPP. This TPPP is the ‘long-type’ which occurs mostly in animals as well as other Opisthokonta. <i>P. tribonematis</i> has a ‘fungal-type’ TPPP, which is found only in some flagellated fungi. These data on Aphelidiomycota TPPP proteins strengthen the correlation between the incidence of p25alpha domain-containing proteins and that of the eukaryotic flagellum/cilium.https://www.mdpi.com/2309-608X/9/3/376<i>Amoeboaphelidium protococcorum</i>AphelidiomycotaflagellumfungiOlpidiomycota<i>Paraphelidium tribonematis</i> |
| spellingShingle | Ferenc Orosz Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum Journal of Fungi <i>Amoeboaphelidium protococcorum</i> Aphelidiomycota flagellum fungi Olpidiomycota <i>Paraphelidium tribonematis</i> |
| title | Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum |
| title_full | Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum |
| title_fullStr | Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum |
| title_full_unstemmed | Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum |
| title_short | Tubulin Polymerization Promoting Proteins (TPPPs) of Aphelidiomycota: Correlation between the Incidence of p25alpha Domain and the Eukaryotic Flagellum |
| title_sort | tubulin polymerization promoting proteins tppps of aphelidiomycota correlation between the incidence of p25alpha domain and the eukaryotic flagellum |
| topic | <i>Amoeboaphelidium protococcorum</i> Aphelidiomycota flagellum fungi Olpidiomycota <i>Paraphelidium tribonematis</i> |
| url | https://www.mdpi.com/2309-608X/9/3/376 |
| work_keys_str_mv | AT ferencorosz tubulinpolymerizationpromotingproteinstpppsofaphelidiomycotacorrelationbetweentheincidenceofp25alphadomainandtheeukaryoticflagellum |