Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance

Polycystic Ovarian Syndrome (PCOS) is the main infertility cause due to metabolic and hormonal dysfunctions of the ovaries. This syndrome is comorbid with insulin resistance and substantially increases the risk of endometrial hyperplasia, obesity, breast cancer, myocardial infarction and stroke. Wom...

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Main Authors: O A Gromova, E A Goncharova, I Yu Torshin, O A Limanova, N V Kerimkulova
Format: Article
Language:Russian
Published: IP Berlin A.V. 2014-02-01
Series:Гинекология
Subjects:
Online Access:https://gynecology.orscience.ru/2079-5831/article/viewFile/28298/pdf
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author O A Gromova
E A Goncharova
I Yu Torshin
O A Limanova
N V Kerimkulova
author_facet O A Gromova
E A Goncharova
I Yu Torshin
O A Limanova
N V Kerimkulova
author_sort O A Gromova
collection DOAJ
description Polycystic Ovarian Syndrome (PCOS) is the main infertility cause due to metabolic and hormonal dysfunctions of the ovaries. This syndrome is comorbid with insulin resistance and substantially increases the risk of endometrial hyperplasia, obesity, breast cancer, myocardial infarction and stroke. Women with PCOS have an increased risk of anovulatory cycles, infertility and miscarriage.One of the promising nutricial directions in the complex treatment of PCOS is the use of myo-inositol. A systematic analysis presented in this paper, showed that oral administration of myo-inositol at a dose of 2-4 g/day helps to reduce insulin resistance, excessive androgen secretion, the risk of hirsutism and acne, normalization of lipid profile and blood pressure. Its reception improves functioning of the reproductive axis in patients with PCOS, normalizes ovulation and formation of mature oocytes. Inclusion of myo-inositol in the process of preparing for the procedure of in vitro fertilization (IVF) can significantly improve the results in patients with PCOS and other disorders associated with infertility.
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spelling doaj.art-89919ff2a02648ceb09049eb283245e92022-12-22T01:49:19ZrusIP Berlin A.V.Гинекология2079-56962079-58312014-02-01161586525428Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistanceO A GromovaE A GoncharovaI Yu TorshinO A LimanovaN V KerimkulovaPolycystic Ovarian Syndrome (PCOS) is the main infertility cause due to metabolic and hormonal dysfunctions of the ovaries. This syndrome is comorbid with insulin resistance and substantially increases the risk of endometrial hyperplasia, obesity, breast cancer, myocardial infarction and stroke. Women with PCOS have an increased risk of anovulatory cycles, infertility and miscarriage.One of the promising nutricial directions in the complex treatment of PCOS is the use of myo-inositol. A systematic analysis presented in this paper, showed that oral administration of myo-inositol at a dose of 2-4 g/day helps to reduce insulin resistance, excessive androgen secretion, the risk of hirsutism and acne, normalization of lipid profile and blood pressure. Its reception improves functioning of the reproductive axis in patients with PCOS, normalizes ovulation and formation of mature oocytes. Inclusion of myo-inositol in the process of preparing for the procedure of in vitro fertilization (IVF) can significantly improve the results in patients with PCOS and other disorders associated with infertility.https://gynecology.orscience.ru/2079-5831/article/viewFile/28298/pdfmyo-inositolpolycystic ovary syndromehyperinsulinemiapreparation for ivfinofert
spellingShingle O A Gromova
E A Goncharova
I Yu Torshin
O A Limanova
N V Kerimkulova
Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance
Гинекология
myo-inositol
polycystic ovary syndrome
hyperinsulinemia
preparation for ivf
inofert
title Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance
title_full Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance
title_fullStr Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance
title_full_unstemmed Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance
title_short Myo-inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance
title_sort myo inositol pregravidal training use prospects in women with polycystic ovary syndrome and insulin resistance
topic myo-inositol
polycystic ovary syndrome
hyperinsulinemia
preparation for ivf
inofert
url https://gynecology.orscience.ru/2079-5831/article/viewFile/28298/pdf
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AT iyutorshin myoinositolpregravidaltraininguseprospectsinwomenwithpolycysticovarysyndromeandinsulinresistance
AT oalimanova myoinositolpregravidaltraininguseprospectsinwomenwithpolycysticovarysyndromeandinsulinresistance
AT nvkerimkulova myoinositolpregravidaltraininguseprospectsinwomenwithpolycysticovarysyndromeandinsulinresistance