SR9009 improves heart function after pressure overload independent of cardiac REV-ERB
The core clock component REV-ERB is essential for heart function. Previous studies show that REV-ERB agonist SR9009 ameliorates heart remodeling in the pressure overload model with transverse aortic constriction (TAC). However, it is unknown whether SR9009 indeed works through cardiac REV-ERB, given...
Main Authors: | Hui Li, Shiyang Song, Chih-liang Tien, Lei Qi, Andrea Graves, Eleni Nasiotis, Thomas P. Burris, Yuanbiao Zhao, Zheng Sun, Lilei Zhang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-07-01
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Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.952114/full |
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