Dexamethasone Attenuates X-Ray-Induced Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle in Breast Tissue and Subsequent Breast Fibrosis
We recently showed that radiation-induced DNA damage in breast adipose tissue increases autotaxin secretion, production of lysophosphatidate (LPA) and expression of LPA<sub>1/2</sub> receptors. We also established that dexamethasone decreases autotaxin production and LPA signaling in non...
Main Authors: | Guanmin Meng, Melinda Wuest, Xiaoyun Tang, Jennifer Dufour, Todd P.W. McMullen, Frank Wuest, David Murray, David N. Brindley |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/4/999 |
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