Imatinib, a New Adjuvant Medical Treatment for Multifocal Villonodular Synovitis Associated to Noonan Syndrome: A Case Report and Literature Review

Imatinib, a New Adjuvant Medical Treatment for Multifocal Villonodular Synovitis Associated to Noonan Syndrome: A Case Report and Literature Review

Noonan syndrome (NS) is an autosomal dominant multisystem disorder caused by the dysregulation of the Rat Sarcoma/Mitogen-activated protein kinase (RAS/MAPK) pathway and characterized by short stature, heart defects, pectus excavatum, webbed neck, learning disabilities, cryptorchidism, and facial dy...

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Bibliographic Details
Main Authors: Romain Dalla-Torre, Vincent Crenn, Pierre Menu, Bertrand Isidor, Pascale Guillot, Benoit Le Goff, Loic Geffroy, Marc Dauty, Alban Fouasson-Chailloux
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Medicine
Subjects:
Noonan syndrome
multifocal villonodular synovitis
Imatinib
joints
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.817873/full

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