Phlebotomus papatasi SP15: mRNA expression variability and amino acid sequence polymorphisms of field populations

Phlebotomus papatasi SP15: mRNA expression variability and amino acid sequence polymorphisms of field populations

Abstract Background The Phlebotomus papatasi salivary protein PpSP15 was shown to protect mice against Leishmania major, suggesting that incorporation of salivary molecules in multi-component vaccines may be a viable strategy for anti-Leishmania vaccines. Methods Here, we investigated PpSP15 predict...

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Bibliographic Details
Main Authors: Marcelo Ramalho-Ortigão, Iliano V. Coutinho-Abreu, Valdir Q. Balbino, Carlos Alberto S. Figueiredo, Rami Mukbel, Hussan Dayem, Hanafi A. Hanafi, Shabaan S. El-Hossary, Emad El-Din Y. Fawaz, Mahmoud Abo-Shehada, David F. Hoel, Gwen Stayback, Mariha Wadsworth, Douglas A. Shoue, Jenica Abrudan, Neil F. Lobo, Andrew R. Mahon, Scott J. Emrich, Shaden Kamhawi, Frank H. Collins, Mary Ann McDowell
Format: Article
Language:English
Published: BMC 2015-05-01
Series:Parasites & Vectors
Subjects:
Sand fly
Saliva
PpSP15
Leishmaniasis
Vaccine
Expression variability
Online Access:https://doi.org/10.1186/s13071-015-0914-2

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