Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events

Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events

Background Familial hypercholesterolemia (FH) may arise from deleterious monogenic variants in FH‐causing genes as well as from a polygenic cause. We evaluated the relationships between monogenic FH and polygenic hypercholesterolemia in influencing the long‐term response to therapy and the risk of a...

書誌詳細
主要な著者:	Laura D’Erasmo, Ilenia Minicocci, Alessia Di Costanzo, Giovanni Pigna, Daniela Commodari, Fabrizio Ceci, Anna Montali, Francesca Brancato, Ilaria Stanca, Antonio Nicolucci, Andrea Ascione, Nicola Galea, Iacopo Carbone, Marco Francone, Marianna Maranghi, Marcello Arca
フォーマット:	論文
言語:	English
出版事項:	Wiley 2021-05-01
シリーズ:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
主題:	atherosclerosis cardiovascular disease genetics hypercholesterolemia therapy
オンライン･アクセス:	https://www.ahajournals.org/doi/10.1161/JAHA.120.018932

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