Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events

Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events

Background Familial hypercholesterolemia (FH) may arise from deleterious monogenic variants in FH‐causing genes as well as from a polygenic cause. We evaluated the relationships between monogenic FH and polygenic hypercholesterolemia in influencing the long‐term response to therapy and the risk of a...

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গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Laura D’Erasmo, Ilenia Minicocci, Alessia Di Costanzo, Giovanni Pigna, Daniela Commodari, Fabrizio Ceci, Anna Montali, Francesca Brancato, Ilaria Stanca, Antonio Nicolucci, Andrea Ascione, Nicola Galea, Iacopo Carbone, Marco Francone, Marianna Maranghi, Marcello Arca
বিন্যাস: প্রবন্ধ
ভাষা:English
প্রকাশিত: Wiley 2021-05-01
মালা:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
বিষয়গুলি:
atherosclerosis
cardiovascular disease
genetics
hypercholesterolemia
therapy
অনলাইন ব্যবহার করুন:https://www.ahajournals.org/doi/10.1161/JAHA.120.018932

আন্তর্জাল

https://www.ahajournals.org/doi/10.1161/JAHA.120.018932

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