Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events
Background Familial hypercholesterolemia (FH) may arise from deleterious monogenic variants in FH‐causing genes as well as from a polygenic cause. We evaluated the relationships between monogenic FH and polygenic hypercholesterolemia in influencing the long‐term response to therapy and the risk of a...
Հիմնական հեղինակներ: | , , , , , , , , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Wiley
2021-05-01
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Շարք: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
Խորագրեր: | |
Առցանց հասանելիություն: | https://www.ahajournals.org/doi/10.1161/JAHA.120.018932 |