Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events
Background Familial hypercholesterolemia (FH) may arise from deleterious monogenic variants in FH‐causing genes as well as from a polygenic cause. We evaluated the relationships between monogenic FH and polygenic hypercholesterolemia in influencing the long‐term response to therapy and the risk of a...
主要な著者: | , , , , , , , , , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Wiley
2021-05-01
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シリーズ: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
主題: | |
オンライン・アクセス: | https://www.ahajournals.org/doi/10.1161/JAHA.120.018932 |