Adjuvant Effects of a New Saponin Analog VSA-1 on Enhancing Homologous and Heterosubtypic Protection by Influenza Virus Vaccination

Adjuvant Effects of a New Saponin Analog VSA-1 on Enhancing Homologous and Heterosubtypic Protection by Influenza Virus Vaccination

Adjuvants can increase the magnitude and durability of the immune response generated by the vaccine antigen. Aluminum salts (Alum) remain the main adjuvant licensed for human use. A few new adjuvants have been licensed for use in human vaccines since the 1990s. QS-21, a mixture of saponin compounds,...

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Bibliographic Details
Main Authors: Noopur Bhatnagar, Ki-Hye Kim, Jeeva Subbiah, Bo Ryoung Park, Pengfei Wang, Harvinder Singh Gill, Bao-Zhong Wang, Sang-Moo Kang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
influenza virus
split vaccine
adjuvant
cross-protection
Online Access:https://www.mdpi.com/2076-393X/10/9/1383

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