Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia
These data describe the phenotypic variability in a large cohort of patients confirmed to have homozygous familial hypercholesterolemia. Herein, we describe the observed relationship of treated low-density lipoprotein cholesterol with age. We also overlay the low-density lipoprotein receptor gene (L...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-06-01
|
| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340916302189 |
| _version_ | 1818158651750219776 |
|---|---|
| author | Frederick J. Raal Barbara Sjouke G. Kees Hovingh Barton F. Isaac |
| author_facet | Frederick J. Raal Barbara Sjouke G. Kees Hovingh Barton F. Isaac |
| author_sort | Frederick J. Raal |
| collection | DOAJ |
| description | These data describe the phenotypic variability in a large cohort of patients confirmed to have homozygous familial hypercholesterolemia. Herein, we describe the observed relationship of treated low-density lipoprotein cholesterol with age. We also overlay the low-density lipoprotein receptor gene (LDLR) functional status with these phenotypic data. A full description of these data is available in our recent study published in Atherosclerosis, “Phenotype Diversity Among Patients With Homozygous Familial Hypercholesterolemia: A Cohort Study” (Raal et al., 2016) [1]. Keywords: Homozygous familial hypercholesterolemia, Cholesterol, Phenotype |
| first_indexed | 2024-12-11T15:33:29Z |
| format | Article |
| id | doaj.art-89a0244b074c41bdbde49b89147fb2f9 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-11T15:33:29Z |
| publishDate | 2016-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-89a0244b074c41bdbde49b89147fb2f92022-12-22T01:00:00ZengElsevierData in Brief2352-34092016-06-01714581462Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemiaFrederick J. Raal0Barbara Sjouke1G. Kees Hovingh2Barton F. Isaac3Department of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Corresponding author.Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, NetherlandsDepartment of Vascular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1100 DD Amsterdam, NetherlandsMedical Affairs, Sanofi Genzyme, 500 Kendall Street, Cambridge, MA 02142, USAThese data describe the phenotypic variability in a large cohort of patients confirmed to have homozygous familial hypercholesterolemia. Herein, we describe the observed relationship of treated low-density lipoprotein cholesterol with age. We also overlay the low-density lipoprotein receptor gene (LDLR) functional status with these phenotypic data. A full description of these data is available in our recent study published in Atherosclerosis, “Phenotype Diversity Among Patients With Homozygous Familial Hypercholesterolemia: A Cohort Study” (Raal et al., 2016) [1]. Keywords: Homozygous familial hypercholesterolemia, Cholesterol, Phenotypehttp://www.sciencedirect.com/science/article/pii/S2352340916302189 |
| spellingShingle | Frederick J. Raal Barbara Sjouke G. Kees Hovingh Barton F. Isaac Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia Data in Brief |
| title | Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia |
| title_full | Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia |
| title_fullStr | Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia |
| title_full_unstemmed | Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia |
| title_short | Retrospective analysis of cohort database: Phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia |
| title_sort | retrospective analysis of cohort database phenotypic variability in a large dataset of patients confirmed to have homozygous familial hypercholesterolemia |
| url | http://www.sciencedirect.com/science/article/pii/S2352340916302189 |
| work_keys_str_mv | AT frederickjraal retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia AT barbarasjouke retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia AT gkeeshovingh retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia AT bartonfisaac retrospectiveanalysisofcohortdatabasephenotypicvariabilityinalargedatasetofpatientsconfirmedtohavehomozygousfamilialhypercholesterolemia |