Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy
Cerebral palsy (CP) is a group of non-progressive disorders of motor function in children resulting from an injury to an immature brain. In addition to abnormal limb and trunk movement, individuals with CP can experience involuntary muscle contractions of the lower facial muscle groups, causing orom...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Toxins |
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| Online Access: | https://www.mdpi.com/2072-6651/14/3/158 |
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| author | Fabiola I. Reyes Hannah A. Shoval Amy Tenaglia Heakyung Kim |
| author_facet | Fabiola I. Reyes Hannah A. Shoval Amy Tenaglia Heakyung Kim |
| author_sort | Fabiola I. Reyes |
| collection | DOAJ |
| description | Cerebral palsy (CP) is a group of non-progressive disorders of motor function in children resulting from an injury to an immature brain. In addition to abnormal limb and trunk movement, individuals with CP can experience involuntary muscle contractions of the lower facial muscle groups, causing oromandibular dystonia (OMD). Contraction of the lateral pterygoids and submandibular muscles depresses the mandible. OMD involving the lateral pterygoids can therefore lead to involuntary jaw opening posture, affecting the ability to feed and speak effectively. We present a case series of five patients with CP and OMD that received novel ultrasound-guided onabotulinumtoxinA to the lateral pterygoid muscles. Our goal was to determine if chemodenervation would improve the mouth-closing ability, thus in turn improving the ability to swallow, chew, manage secretions, and communicate. We describe this unique injection method and report a subjective improvement in eating abilities and communication, in addition to a positive upward trend in most patients’ weights, with no significant adverse side effects. |
| first_indexed | 2024-03-09T12:22:56Z |
| format | Article |
| id | doaj.art-89a05c9edf8a4926b7a19fd28b341bfe |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-03-09T12:22:56Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-89a05c9edf8a4926b7a19fd28b341bfe2023-11-30T22:38:49ZengMDPI AGToxins2072-66512022-02-0114315810.3390/toxins14030158Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral PalsyFabiola I. Reyes0Hannah A. Shoval1Amy Tenaglia2Heakyung Kim3Scottish Rite for Children, Dallas, TX 75219, USAChildren’s Specialized Hospital, Clifton, NJ 07013, USADepartment of Rehabilitation and Regenerative Medicine, Columbia University Irving Medical Center, New York, NY 10032, USADepartment of Rehabilitation and Regenerative Medicine, Columbia University Irving Medical Center, New York, NY 10032, USACerebral palsy (CP) is a group of non-progressive disorders of motor function in children resulting from an injury to an immature brain. In addition to abnormal limb and trunk movement, individuals with CP can experience involuntary muscle contractions of the lower facial muscle groups, causing oromandibular dystonia (OMD). Contraction of the lateral pterygoids and submandibular muscles depresses the mandible. OMD involving the lateral pterygoids can therefore lead to involuntary jaw opening posture, affecting the ability to feed and speak effectively. We present a case series of five patients with CP and OMD that received novel ultrasound-guided onabotulinumtoxinA to the lateral pterygoid muscles. Our goal was to determine if chemodenervation would improve the mouth-closing ability, thus in turn improving the ability to swallow, chew, manage secretions, and communicate. We describe this unique injection method and report a subjective improvement in eating abilities and communication, in addition to a positive upward trend in most patients’ weights, with no significant adverse side effects.https://www.mdpi.com/2072-6651/14/3/158oromandibular dystonialateral pterygoidcerebral palsyultrasound guidancebotulinum toxin |
| spellingShingle | Fabiola I. Reyes Hannah A. Shoval Amy Tenaglia Heakyung Kim Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy Toxins oromandibular dystonia lateral pterygoid cerebral palsy ultrasound guidance botulinum toxin |
| title | Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy |
| title_full | Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy |
| title_fullStr | Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy |
| title_full_unstemmed | Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy |
| title_short | Ultrasound-Guided OnabotulinumtoxinA Injections to Treat Oromandibular Dystonia in Cerebral Palsy |
| title_sort | ultrasound guided onabotulinumtoxina injections to treat oromandibular dystonia in cerebral palsy |
| topic | oromandibular dystonia lateral pterygoid cerebral palsy ultrasound guidance botulinum toxin |
| url | https://www.mdpi.com/2072-6651/14/3/158 |
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