REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION
Sequence-specific (regulatory) transcription factors selectively regulate the transcription levels of different sets of eukaryotic genes depending on cell type, developmental stage, and external signals. Recruitment of the RNA-polymerase II transcription initiation apparatus to promoters by regulato...
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Format: | Article |
Language: | English |
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Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2015-01-01
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Series: | Вавиловский журнал генетики и селекции |
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Online Access: | https://vavilov.elpub.ru/jour/article/view/255 |
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author | V. M. Merkulov T. I. Merkulova |
author_facet | V. M. Merkulov T. I. Merkulova |
author_sort | V. M. Merkulov |
collection | DOAJ |
description | Sequence-specific (regulatory) transcription factors selectively regulate the transcription levels of different sets of eukaryotic genes depending on cell type, developmental stage, and external signals. Recruitment of the RNA-polymerase II transcription initiation apparatus to promoters by regulatory transcription factors is generally recognized as the key mechanism responsible for transcription control by these proteins. However, recent data indicate that regulatory transcription factors may also be involved in transcription elongation control. These data are summarized here. |
first_indexed | 2024-03-07T16:08:15Z |
format | Article |
id | doaj.art-89a30f78b73f4b18a8a2edf973af5205 |
institution | Directory Open Access Journal |
issn | 2500-3259 |
language | English |
last_indexed | 2024-04-24T11:09:43Z |
publishDate | 2015-01-01 |
publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
record_format | Article |
series | Вавиловский журнал генетики и селекции |
spelling | doaj.art-89a30f78b73f4b18a8a2edf973af52052024-04-11T15:30:54ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01182329337239REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTIONV. M. Merkulov0T. I. Merkulova1Institute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaSequence-specific (regulatory) transcription factors selectively regulate the transcription levels of different sets of eukaryotic genes depending on cell type, developmental stage, and external signals. Recruitment of the RNA-polymerase II transcription initiation apparatus to promoters by regulatory transcription factors is generally recognized as the key mechanism responsible for transcription control by these proteins. However, recent data indicate that regulatory transcription factors may also be involved in transcription elongation control. These data are summarized here.https://vavilov.elpub.ru/jour/article/view/255rna-polymerase iipromoter-proximal pausingtranscription factorspositive transcription elongation factor b (p-tefb) |
spellingShingle | V. M. Merkulov T. I. Merkulova REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION Вавиловский журнал генетики и селекции rna-polymerase ii promoter-proximal pausing transcription factors positive transcription elongation factor b (p-tefb) |
title | REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION |
title_full | REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION |
title_fullStr | REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION |
title_full_unstemmed | REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION |
title_short | REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION |
title_sort | regulatory transcription factors may participate in post initiation control of transcription |
topic | rna-polymerase ii promoter-proximal pausing transcription factors positive transcription elongation factor b (p-tefb) |
url | https://vavilov.elpub.ru/jour/article/view/255 |
work_keys_str_mv | AT vmmerkulov regulatorytranscriptionfactorsmayparticipateinpostinitiationcontroloftranscription AT timerkulova regulatorytranscriptionfactorsmayparticipateinpostinitiationcontroloftranscription |