REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION

Sequence-specific (regulatory) transcription factors selectively regulate the transcription levels of different sets of eukaryotic genes depending on cell type, developmental stage, and external signals. Recruitment of the RNA-polymerase II transcription initiation apparatus to promoters by regulato...

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Main Authors: V. M. Merkulov, T. I. Merkulova
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2015-01-01
Series:Вавиловский журнал генетики и селекции
Subjects:
Online Access:https://vavilov.elpub.ru/jour/article/view/255
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author V. M. Merkulov
T. I. Merkulova
author_facet V. M. Merkulov
T. I. Merkulova
author_sort V. M. Merkulov
collection DOAJ
description Sequence-specific (regulatory) transcription factors selectively regulate the transcription levels of different sets of eukaryotic genes depending on cell type, developmental stage, and external signals. Recruitment of the RNA-polymerase II transcription initiation apparatus to promoters by regulatory transcription factors is generally recognized as the key mechanism responsible for transcription control by these proteins. However, recent data indicate that regulatory transcription factors may also be involved in transcription elongation control. These data are summarized here.
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language English
last_indexed 2024-04-24T11:09:43Z
publishDate 2015-01-01
publisher Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
record_format Article
series Вавиловский журнал генетики и селекции
spelling doaj.art-89a30f78b73f4b18a8a2edf973af52052024-04-11T15:30:54ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01182329337239REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTIONV. M. Merkulov0T. I. Merkulova1Institute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaSequence-specific (regulatory) transcription factors selectively regulate the transcription levels of different sets of eukaryotic genes depending on cell type, developmental stage, and external signals. Recruitment of the RNA-polymerase II transcription initiation apparatus to promoters by regulatory transcription factors is generally recognized as the key mechanism responsible for transcription control by these proteins. However, recent data indicate that regulatory transcription factors may also be involved in transcription elongation control. These data are summarized here.https://vavilov.elpub.ru/jour/article/view/255rna-polymerase iipromoter-proximal pausingtranscription factorspositive transcription elongation factor b (p-tefb)
spellingShingle V. M. Merkulov
T. I. Merkulova
REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION
Вавиловский журнал генетики и селекции
rna-polymerase ii
promoter-proximal pausing
transcription factors
positive transcription elongation factor b (p-tefb)
title REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION
title_full REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION
title_fullStr REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION
title_full_unstemmed REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION
title_short REGULATORY TRANSCRIPTION FACTORS MAY PARTICIPATE IN POST-INITIATION CONTROL OF TRANSCRIPTION
title_sort regulatory transcription factors may participate in post initiation control of transcription
topic rna-polymerase ii
promoter-proximal pausing
transcription factors
positive transcription elongation factor b (p-tefb)
url https://vavilov.elpub.ru/jour/article/view/255
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