Role of HMGB1 in an Animal Model of Vascular Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion

Role of HMGB1 in an Animal Model of Vascular Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion

The pathophysiology of vascular cognitive impairment (VCI) is associated with chronic cerebral hypoperfusion (CCH). Increased high-mobility group box protein 1 (HMGB1), a nonhistone protein involved in injury and inflammation, has been established in the acute phase of CCH. However, the role of HMGB...

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Bibliographic Details
Main Authors:	Amelia Nur Vidyanti, Jia-Yu Hsieh, Kun-Ju Lin, Yao-Ching Fang, Ismail Setyopranoto, Chaur-Jong Hu
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Series:	International Journal of Molecular Sciences
Subjects:	vascular cognitive impairment chronic cerebral hypoperfusion modified bilateral common carotid artery occlusion hmgb1
Online Access:	https://www.mdpi.com/1422-0067/21/6/2176

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