MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury.

MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury.

Loss of retinal ganglion cells (RGCs) in optic neuropathies results in permanent partial or complete blindness. Myocyte enhancer factor 2 (MEF2) transcription factors have been shown to play a pivotal role in neuronal systems, and in particular MEF2A knockout was shown to enhance RGC survival after...

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Bibliographic Details
Main Authors: Xin Xia, Caroline Y Yu, Minjuan Bian, Catalina B Sun, Bogdan Tanasa, Kun-Che Chang, Dawn M Bruffett, Hrishikesh Thakur, Sahil H Shah, Cara Knasel, Evan G Cameron, Michael S Kapiloff, Jeffrey L Goldberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242884

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