Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the <sup>64</sup>Cu-Labelling of Immunoconjugates
The development of <sup>64</sup>Cu-based immuno-PET radiotracers requires the use of copper-specific bifunctional chelators (BFCs) that contain functional groups allowing both convenient bioconjugation and stable copper complexes to limit in vivo bioreduction, transmetallation and/or tra...
Main Authors: | Aurélie Maisonial-Besset, Tiffany Witkowski, Mercedes Quintana, Sophie Besse, Vincent Gaumet, Axel Cordonnier, Cyrille Alliot, Aurélien Vidal, Caroline Denevault-Sabourin, Sébastien Tarrit, Sophie Levesque, Elisabeth Miot-Noirault, Jean-Michel Chezal |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/28/1/75 |
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