Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients
Breast cancer is a severe public health problem, and early treatment with powerful anticancer drugs is critical for success. The researchers investigated the clinical results of a novel screening tool termed Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) in breast cancer patients in this cli...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/15/10/2764 |
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| author | Shih-Hsin Tu Wan-Ting Huang Chee Ho Chew Amanda Lin Chen Shou-Tung Chen Jin-Hua Chen Yi-Chen Hsieh Chien-Chung Chen |
| author_facet | Shih-Hsin Tu Wan-Ting Huang Chee Ho Chew Amanda Lin Chen Shou-Tung Chen Jin-Hua Chen Yi-Chen Hsieh Chien-Chung Chen |
| author_sort | Shih-Hsin Tu |
| collection | DOAJ |
| description | Breast cancer is a severe public health problem, and early treatment with powerful anticancer drugs is critical for success. The researchers investigated the clinical results of a novel screening tool termed Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) in breast cancer patients in this clinical investigation. In all trial participants, the MTAM-HFA was utilized to identify active medicines for the treatment of breast cancer. The MTAM-HFA was shown to be extremely useful in predicting patient response to anticancer medication therapy in this study. Furthermore, the substantial association between the MTAM-HFA screening outcome and the clinical outcome of the respective patients emphasizes the promise of this unique screening technology in discovering effective anticancer medication combinations for the treatment of breast cancer. These findings indicate that the MTAM-HFA has clinical significance and might be a valuable tool in the development of tailored therapy for cancer care. This study provides helpful information for physicians and scientists working on breast cancer therapy research. The potential benefits of employing MTAM-HFA to find accurate therapies for breast cancer patients might lead to enhanced personalized medicine approaches to cancer care, resulting in better patient outcomes. Overall, the MTAM-HFA screening approach has the potential to revolutionize customized cancer therapy, providing hope to both patients and physicians. |
| first_indexed | 2024-03-11T03:51:50Z |
| format | Article |
| id | doaj.art-89b75b6ccb2046cb9b5cf474bc483f38 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-11T03:51:50Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-89b75b6ccb2046cb9b5cf474bc483f382023-11-18T00:48:35ZengMDPI AGCancers2072-66942023-05-011510276410.3390/cancers15102764Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer PatientsShih-Hsin Tu0Wan-Ting Huang1Chee Ho Chew2Amanda Lin Chen3Shou-Tung Chen4Jin-Hua Chen5Yi-Chen Hsieh6Chien-Chung Chen7Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, TaiwanGraduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei 11052, TaiwanGraduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei 11052, TaiwanTranslational Autoinflammatory Disease Section (TADS), Laboratory of Clinical Immunology and Microbiology (LCIM), National Institutes of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USAComprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua 50094, TaiwanGraduate Institute of Data Science, College of Management, Taipei Medical University, Taipei 11052, TaiwanPh.D. Program in Medical Neuroscience, Taipei Medical University, Taipei 250, TaiwanGraduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei 11052, TaiwanBreast cancer is a severe public health problem, and early treatment with powerful anticancer drugs is critical for success. The researchers investigated the clinical results of a novel screening tool termed Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) in breast cancer patients in this clinical investigation. In all trial participants, the MTAM-HFA was utilized to identify active medicines for the treatment of breast cancer. The MTAM-HFA was shown to be extremely useful in predicting patient response to anticancer medication therapy in this study. Furthermore, the substantial association between the MTAM-HFA screening outcome and the clinical outcome of the respective patients emphasizes the promise of this unique screening technology in discovering effective anticancer medication combinations for the treatment of breast cancer. These findings indicate that the MTAM-HFA has clinical significance and might be a valuable tool in the development of tailored therapy for cancer care. This study provides helpful information for physicians and scientists working on breast cancer therapy research. The potential benefits of employing MTAM-HFA to find accurate therapies for breast cancer patients might lead to enhanced personalized medicine approaches to cancer care, resulting in better patient outcomes. Overall, the MTAM-HFA screening approach has the potential to revolutionize customized cancer therapy, providing hope to both patients and physicians.https://www.mdpi.com/2072-6694/15/10/2764breast cancerMicrotube Array Membrane Hollow Fiber Assay (MTAM-HFA)personalized medicineanti-cancer drug screening |
| spellingShingle | Shih-Hsin Tu Wan-Ting Huang Chee Ho Chew Amanda Lin Chen Shou-Tung Chen Jin-Hua Chen Yi-Chen Hsieh Chien-Chung Chen Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients Cancers breast cancer Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) personalized medicine anti-cancer drug screening |
| title | Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients |
| title_full | Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients |
| title_fullStr | Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients |
| title_full_unstemmed | Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients |
| title_short | Unveiling the Power of Anticancer Drug Screening: A Clinical Case Study Comparing the Effectiveness of Hollow Fiber Assay Microtube Array Membrane (MTAM-HFA) in Breast Cancer Patients |
| title_sort | unveiling the power of anticancer drug screening a clinical case study comparing the effectiveness of hollow fiber assay microtube array membrane mtam hfa in breast cancer patients |
| topic | breast cancer Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA) personalized medicine anti-cancer drug screening |
| url | https://www.mdpi.com/2072-6694/15/10/2764 |
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