CircLDLR acts as a sponge for miR-667-5p to regulate SIRT1 expression in non-alcoholic fatty liver disease

CircLDLR acts as a sponge for miR-667-5p to regulate SIRT1 expression in non-alcoholic fatty liver disease

Abstract Background Non-alcoholic fatty liver (NAFLD) is a complex metabolic disease characterized by fatty degeneration of hepatocytes. Circular RNAs (circRNAs) have been reported to be essential for (NAFLD progression. The potential mechanism of circRNA low-density lipoprotein receptor (circLDLR)...

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Bibliographic Details
Main Authors: Xinlu Yuan, Yanyan Li, Song Wen, Chenglin Xu, Congcong Wang, Yanju He, Ligang Zhou
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Lipids in Health and Disease
Subjects:
Non-alcoholic fatty liver disease
circRNAs
SIRT1
miR-667-5p
Autophagy
Online Access:https://doi.org/10.1186/s12944-022-01740-9

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