Macrophage Tim-3 maintains intestinal homeostasis in DSS-induced colitis by suppressing neutrophil necroptosis

Macrophage Tim-3 maintains intestinal homeostasis in DSS-induced colitis by suppressing neutrophil necroptosis

T-cell immunoglobulin domain and mucin domain-3 (Tim-3) is a versatile immunomodulator that protects against intestinal inflammation. Necroptosis is a type of cell death that regulates intestinal homeostasis and inflammation. The mechanism(s) underlying the protective role of macrophage Tim-3 in int...

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Bibliographic Details
Main Authors: Fangfei Wang, Feng Zhou, Jianxiang Peng, Hao Chen, Jinliang Xie, Cong Liu, Huifang Xiong, Sihai Chen, Guohui Xue, Xiaojiang Zhou, Yong Xie
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Redox Biology
Subjects:
Tim-3
Necroptosis
Neutrophil
Macrophage
ROS
Inflammatory bowel disease
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172400048X

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