Drosophila HP1c is regulated by an auto-regulatory feedback loop through its binding partner Woc.

Drosophila HP1c is regulated by an auto-regulatory feedback loop through its binding partner Woc.

HP1 is a major component of chromatin and regulates gene expression through its binding to methylated histone H3. Most eukaryotes express at least three isoforms of HP1 with similar domain architecture. However, despite the common specificity for methylated histone H3, the three HP1 isoforms bind to...

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Bibliographic Details
Main Authors: Jochen Abel, Ragnhild Eskeland, Grazia D Raffa, Elisabeth Kremmer, Axel Imhof
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19352434/pdf/?tool=EBI

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