The relationship between the parameters of microcirculation and the lung function in bronchial asthma in children
Among the chronic nonspecific lung diseases, bronchial asthma (BA) takes the leading place. BA in children is primarily diagnosed on the basis of clinical manifestations, methods of functional diagnosis, which allows you to verify the disease and assess the severity of the flow. An important role in t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
2018-09-01
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| Series: | Сеченовский вестник |
| Subjects: | |
| Online Access: | https://www.sechenovmedj.com/jour/article/view/69 |
| _version_ | 1797873659094761472 |
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| author | N. I. Lozko N. G. Kolosova N. A. Geppe V. D. Denisova |
| author_facet | N. I. Lozko N. G. Kolosova N. A. Geppe V. D. Denisova |
| author_sort | N. I. Lozko |
| collection | DOAJ |
| description | Among the chronic nonspecific lung diseases, bronchial asthma (BA) takes the leading place. BA in children is primarily diagnosed on the basis of clinical manifestations, methods of functional diagnosis, which allows you to verify the disease and assess the severity of the flow. An important role in the pathogenesis of asthma is played by the microcirculation system, affecting the course and progression of the disease. Dysfunction of microcirculation system supports chronic inflammatory process, affecting the level of perfusion, metabolism and gas exchange. The study was carried out on the basis of the University Children's Clinical Hospital (pulmonology department) of the First Moscow State Medical University named after I.M. Sechenov Ministry of Health of Russia (Sechenovsky University). 100 children aged 6-17 years with asthma were examined. Based on the study of the nature of microcirculatory disorders by the LDF method in bronchial asthma in children with different severity of the disease, correlation links between microcirculation indices, clinical manifestations and external respiration function (spirometry and computer bronchophonography) in children have been revealed. The observed decrease in microcirculation during the exacerbation of asthma is short-term and insignificant in mild severity and is longer and more significant with moderate BA, which supports a chronic inflammatory process in the bronchi. Correction of disorders of microcirculation is an important link in the therapeutic approach. |
| first_indexed | 2024-04-10T01:19:44Z |
| format | Article |
| id | doaj.art-89cf4aad792e4b38b067434e74a4dca3 |
| institution | Directory Open Access Journal |
| issn | 2218-7332 2658-3348 |
| language | Russian |
| last_indexed | 2024-04-10T01:19:44Z |
| publishDate | 2018-09-01 |
| publisher | Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) |
| record_format | Article |
| series | Сеченовский вестник |
| spelling | doaj.art-89cf4aad792e4b38b067434e74a4dca32023-03-13T09:51:33ZrusFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Сеченовский вестник2218-73322658-33482018-09-0103303510.47093/2218-7332_2018.3.30-3568The relationship between the parameters of microcirculation and the lung function in bronchial asthma in childrenN. I. Lozko0N. G. Kolosova1N. A. Geppe2V. D. Denisova3I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)Among the chronic nonspecific lung diseases, bronchial asthma (BA) takes the leading place. BA in children is primarily diagnosed on the basis of clinical manifestations, methods of functional diagnosis, which allows you to verify the disease and assess the severity of the flow. An important role in the pathogenesis of asthma is played by the microcirculation system, affecting the course and progression of the disease. Dysfunction of microcirculation system supports chronic inflammatory process, affecting the level of perfusion, metabolism and gas exchange. The study was carried out on the basis of the University Children's Clinical Hospital (pulmonology department) of the First Moscow State Medical University named after I.M. Sechenov Ministry of Health of Russia (Sechenovsky University). 100 children aged 6-17 years with asthma were examined. Based on the study of the nature of microcirculatory disorders by the LDF method in bronchial asthma in children with different severity of the disease, correlation links between microcirculation indices, clinical manifestations and external respiration function (spirometry and computer bronchophonography) in children have been revealed. The observed decrease in microcirculation during the exacerbation of asthma is short-term and insignificant in mild severity and is longer and more significant with moderate BA, which supports a chronic inflammatory process in the bronchi. Correction of disorders of microcirculation is an important link in the therapeutic approach.https://www.sechenovmedj.com/jour/article/view/69bronchial asthmamicrocirculationchildrenlung function respirationcontrol of disease |
| spellingShingle | N. I. Lozko N. G. Kolosova N. A. Geppe V. D. Denisova The relationship between the parameters of microcirculation and the lung function in bronchial asthma in children Сеченовский вестник bronchial asthma microcirculation children lung function respiration control of disease |
| title | The relationship between the parameters of microcirculation and the lung function in bronchial asthma in children |
| title_full | The relationship between the parameters of microcirculation and the lung function in bronchial asthma in children |
| title_fullStr | The relationship between the parameters of microcirculation and the lung function in bronchial asthma in children |
| title_full_unstemmed | The relationship between the parameters of microcirculation and the lung function in bronchial asthma in children |
| title_short | The relationship between the parameters of microcirculation and the lung function in bronchial asthma in children |
| title_sort | relationship between the parameters of microcirculation and the lung function in bronchial asthma in children |
| topic | bronchial asthma microcirculation children lung function respiration control of disease |
| url | https://www.sechenovmedj.com/jour/article/view/69 |
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