Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes

Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes

The presence of lymph node metastasis (LNM) affects treatment strategy decisions in T1NxM0 colorectal cancer (CRC), but the currently used clinicopathological-based risk stratification cannot predict LNM accurately. In this study, we detected proteins in formalin-fixed paraffin-embedded (FFPE) tumor...

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Bibliographic Details
Main Authors: Aojia Zhuang, Aobo Zhuang, Yijiao Chen, Zhaoyu Qin, Dexiang Zhu, Li Ren, Ye Wei, Pengyang Zhou, Xuetong Yue, Fuchu He, Jianmin Xu, Chen Ding
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
Subjects:
T1 colorectal cancer
lymph nodes metastasis
proteomics
machine learning
Online Access:https://elifesciences.org/articles/82959

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