Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma
Purpose: The aim of this study was to evaluate the sleep quality of older patients with multiple myeloma before and after chemotherapy and investigate factors affecting sleep quality. Materials and Methods: A total of 108 patients with newly diagnosed multiple myeloma were included in the study. Ge...
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| Format: | Article |
| Language: | English |
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Cukurova University
2021-12-01
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| Series: | Cukurova Medical Journal |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1903140 |
| _version_ | 1797908050892292096 |
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| author | Mahmut Bakır Koyuncu Çağatay Çavuşoğlu Anıl Tombak Mehmet Ali Uçar Aydan Akdeniz Eyüp Naci Tiftik |
| author_facet | Mahmut Bakır Koyuncu Çağatay Çavuşoğlu Anıl Tombak Mehmet Ali Uçar Aydan Akdeniz Eyüp Naci Tiftik |
| author_sort | Mahmut Bakır Koyuncu |
| collection | DOAJ |
| description | Purpose: The aim of this study was to evaluate the sleep quality of older patients with multiple myeloma before and after chemotherapy and investigate factors affecting sleep quality.
Materials and Methods: A total of 108 patients with newly diagnosed multiple myeloma were included in the study. Geriatric 8 (G8) and Pittsburgh Sleep Quality Index scores were calculated for the patients at the time of diagnosis, and the changes in these scores were evaluated after three cycles of chemotherapy.
Results: At the time of diagnosis, 63 (58.3%) of the patients had sleep disturbances. The sleep disturbance rate decreased to 41.7% after chemotherapy. There was no statistically significant difference in the total G8 score before and after treatment. In logistic regression analyses, the serum calcium level, pre-treatment G8 score, and response to chemotherapy were predictors of sleep quality. Increases in sleep quality were significantly higher in patients with good responses to chemotherapy.
Conclusion: Sleep disturbances are a common problem in older patients with multiple myeloma. Our study demonstrated that sleep quality increased with chemotherapy, and patients with low sleep quality had worse responses to treatment. Therefore, there is a need for measures and treatments to increase the sleep quality of these patients. |
| first_indexed | 2024-04-10T10:46:39Z |
| format | Article |
| id | doaj.art-89d22d73aa5c4621b43df5a102680dfb |
| institution | Directory Open Access Journal |
| issn | 2602-3040 |
| language | English |
| last_indexed | 2024-04-10T10:46:39Z |
| publishDate | 2021-12-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Cukurova Medical Journal |
| spelling | doaj.art-89d22d73aa5c4621b43df5a102680dfb2023-02-15T16:20:17ZengCukurova UniversityCukurova Medical Journal2602-30402021-12-014641574158048Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myelomaMahmut Bakır Koyuncu0Çağatay Çavuşoğlu1Anıl Tombak2Mehmet Ali Uçar3Aydan Akdeniz4Eyüp Naci Tiftik5Adana City Training and Research HospitalSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, ŞANLIURFA MEHMET AKİF İNAN SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİMERSIN UNIVERSITY, SCHOOL OF MEDICINECUKUROVA UNIVERSITY, FACULTY OF MEDICINEMERSIN UNIVERSITY, SCHOOL OF MEDICINEMERSIN UNIVERSITY, SCHOOL OF MEDICINEPurpose: The aim of this study was to evaluate the sleep quality of older patients with multiple myeloma before and after chemotherapy and investigate factors affecting sleep quality. Materials and Methods: A total of 108 patients with newly diagnosed multiple myeloma were included in the study. Geriatric 8 (G8) and Pittsburgh Sleep Quality Index scores were calculated for the patients at the time of diagnosis, and the changes in these scores were evaluated after three cycles of chemotherapy. Results: At the time of diagnosis, 63 (58.3%) of the patients had sleep disturbances. The sleep disturbance rate decreased to 41.7% after chemotherapy. There was no statistically significant difference in the total G8 score before and after treatment. In logistic regression analyses, the serum calcium level, pre-treatment G8 score, and response to chemotherapy were predictors of sleep quality. Increases in sleep quality were significantly higher in patients with good responses to chemotherapy. Conclusion: Sleep disturbances are a common problem in older patients with multiple myeloma. Our study demonstrated that sleep quality increased with chemotherapy, and patients with low sleep quality had worse responses to treatment. Therefore, there is a need for measures and treatments to increase the sleep quality of these patients.https://dergipark.org.tr/tr/download/article-file/1903140multiple myelomasleep qualitygeriatric scoresmultiple myelomuyku kalitesigeriatrik değerlendirme |
| spellingShingle | Mahmut Bakır Koyuncu Çağatay Çavuşoğlu Anıl Tombak Mehmet Ali Uçar Aydan Akdeniz Eyüp Naci Tiftik Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma Cukurova Medical Journal multiple myeloma sleep quality geriatric scores multiple myelom uyku kalitesi geriatrik değerlendirme |
| title | Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma |
| title_full | Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma |
| title_fullStr | Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma |
| title_full_unstemmed | Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma |
| title_short | Changes in sleep quality and geriatric-8 (G8) score with chemotherapy in older patients with multiple myeloma |
| title_sort | changes in sleep quality and geriatric 8 g8 score with chemotherapy in older patients with multiple myeloma |
| topic | multiple myeloma sleep quality geriatric scores multiple myelom uyku kalitesi geriatrik değerlendirme |
| url | https://dergipark.org.tr/tr/download/article-file/1903140 |
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