Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions

With the advent of large language models (LLMs), the artificial intelligence revolution in medicine and radiology is now more tangible than ever. Every day, an increasingly large number of articles are published that utilize LLMs in radiology. To adopt and safely implement this new technology in the...

Full description

Bibliographic Details
Main Authors: Tugba Akinci D’Antonoli, Arnaldo Stanzione, Christian Bluethgen, Federica Vernuccio, Lorenzo Ugga, Michail E. Klontzas, Renato Cuocolo, Roberto Cannella, Burak Koçak
Format: Article
Language:English
Published: Galenos Publishing House 2024-03-01
Series:Diagnostic and Interventional Radiology
Subjects:
Online Access: http://www.dirjournal.org/archives/archive-detail/article-preview/large-language-models-in-radiology-fundamentals-ap/62426
_version_ 1797268918620913664
author Tugba Akinci D’Antonoli
Arnaldo Stanzione
Christian Bluethgen
Federica Vernuccio
Lorenzo Ugga
Michail E. Klontzas
Renato Cuocolo
Roberto Cannella
Burak Koçak
author_facet Tugba Akinci D’Antonoli
Arnaldo Stanzione
Christian Bluethgen
Federica Vernuccio
Lorenzo Ugga
Michail E. Klontzas
Renato Cuocolo
Roberto Cannella
Burak Koçak
author_sort Tugba Akinci D’Antonoli
collection DOAJ
description With the advent of large language models (LLMs), the artificial intelligence revolution in medicine and radiology is now more tangible than ever. Every day, an increasingly large number of articles are published that utilize LLMs in radiology. To adopt and safely implement this new technology in the field, radiologists should be familiar with its key concepts, understand at least the technical basics, and be aware of the potential risks and ethical considerations that come with it. In this review article, the authors provide an overview of the LLMs that might be relevant to the radiology community and include a brief discussion of their short history, technical basics, ChatGPT, prompt engineering, potential applications in medicine and radiology, advantages, disadvantages and risks, ethical and regulatory considerations, and future directions.
first_indexed 2024-04-25T01:40:07Z
format Article
id doaj.art-89d8a0da23854097922bd69b72ea4fcc
institution Directory Open Access Journal
issn 1305-3825
1305-3612
language English
last_indexed 2024-04-25T01:40:07Z
publishDate 2024-03-01
publisher Galenos Publishing House
record_format Article
series Diagnostic and Interventional Radiology
spelling doaj.art-89d8a0da23854097922bd69b72ea4fcc2024-03-08T07:38:32ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122024-03-01302809010.4274/dir.2023.23241713049054Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directionsTugba Akinci D’Antonoli0Arnaldo Stanzione1Christian Bluethgen2Federica Vernuccio3Lorenzo Ugga4Michail E. Klontzas5Renato Cuocolo6Roberto Cannella7Burak Koçak8 Cantonal Hospital Baselland, Institute of Radiology and Nuclear Medicine, Liestal, Switzerland University of Naples Federico II, Department of Advanced Biomedical Sciences, Naples, Italy University Hospital Zurich, University of Zurich, Institute for Diagnostic and Interventional Radiology, Zurich, Switzerland University Hospital of Padova, Department of Radiology, Padova, Italy University of Naples Federico II, Department of Advanced Biomedical Sciences, Naples, Italy Department of Medical Imaging, University Hospital of Heraklion, Crete, Greece & Department of Radiology, University of Crete, Heraklion, Crete, Greece & Computational Biomedicine Laboratory, Institute of Computer Science, FORTH, Heraklion, Crete, Greece University of Salerno, Department of Medicine, Surgery and Dentistry, Baronissi, Italy University of Palermo, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Section of Radiology, Palermo, Italy University of Health Sciences, Basakşehir Çam and Sakura City Hospital, Clinic of Radiology, İstanbul, Türkiye With the advent of large language models (LLMs), the artificial intelligence revolution in medicine and radiology is now more tangible than ever. Every day, an increasingly large number of articles are published that utilize LLMs in radiology. To adopt and safely implement this new technology in the field, radiologists should be familiar with its key concepts, understand at least the technical basics, and be aware of the potential risks and ethical considerations that come with it. In this review article, the authors provide an overview of the LLMs that might be relevant to the radiology community and include a brief discussion of their short history, technical basics, ChatGPT, prompt engineering, potential applications in medicine and radiology, advantages, disadvantages and risks, ethical and regulatory considerations, and future directions. http://www.dirjournal.org/archives/archive-detail/article-preview/large-language-models-in-radiology-fundamentals-ap/62426 large language modelsnatural language processingartificial intelligencedeep learningchatgpt
spellingShingle Tugba Akinci D’Antonoli
Arnaldo Stanzione
Christian Bluethgen
Federica Vernuccio
Lorenzo Ugga
Michail E. Klontzas
Renato Cuocolo
Roberto Cannella
Burak Koçak
Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions
Diagnostic and Interventional Radiology
large language models
natural language processing
artificial intelligence
deep learning
chatgpt
title Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions
title_full Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions
title_fullStr Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions
title_full_unstemmed Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions
title_short Large language models in radiology: fundamentals, applications, ethical considerations, risks, and future directions
title_sort large language models in radiology fundamentals applications ethical considerations risks and future directions
topic large language models
natural language processing
artificial intelligence
deep learning
chatgpt
url http://www.dirjournal.org/archives/archive-detail/article-preview/large-language-models-in-radiology-fundamentals-ap/62426
work_keys_str_mv AT tugbaakincidantonoli largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT arnaldostanzione largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT christianbluethgen largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT federicavernuccio largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT lorenzougga largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT michaileklontzas largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT renatocuocolo largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT robertocannella largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections
AT burakkocak largelanguagemodelsinradiologyfundamentalsapplicationsethicalconsiderationsrisksandfuturedirections