Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicine
Background: According to the reverse pharmacological method, traditional medicine has a good source of information for discovering new drug candidates. Polycystic ovarian syndrome (PCOS) is the most common cause of endocrine disorder and infertility among women of reproductive age. This syndrome is...
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| Format: | Article |
| Language: | English |
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Institue of Medicinal Plants, ACECR
2022-09-01
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| Series: | Journal of Medicinal Plants |
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| Online Access: | http://jmp.ir/article-1-3393-en.html |
| _version_ | 1797957702779928576 |
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| author | Najmeh Dehparvar Fatemeh Alijaniha Seyyed Ali Mozaffarpur Amir Niasari-Naslaji Zahra Bahaedin Ahia Garshasbi Mohammad Gholami-Fesharak Mohsen Naseri |
| author_facet | Najmeh Dehparvar Fatemeh Alijaniha Seyyed Ali Mozaffarpur Amir Niasari-Naslaji Zahra Bahaedin Ahia Garshasbi Mohammad Gholami-Fesharak Mohsen Naseri |
| author_sort | Najmeh Dehparvar |
| collection | DOAJ |
| description | Background: According to the reverse pharmacological method, traditional medicine has a good source of information for discovering new drug candidates. Polycystic ovarian syndrome (PCOS) is the most common cause of endocrine disorder and infertility among women of reproductive age. This syndrome is commonly treated by oral contraceptive pills; however, it could be associated with side effects. Objective: The purpose of this study was to identify and prioritize medicinal plants proposed by Persian medicine (PM) for the treatment of PCOS. Methods: The first step was to find out the most relevant keywords to the symptoms of PCOS among five authentic PM manuscripts because there was no medical term called PCOS in PM texts. According to those keywords, all materia medicas that was described in the selected books were recorded. Each materia medica received scores based on specific criteria. The scores were used to prioritize medicaments. Results: Ferula assa-foetida L., Tanacetum parthenium L., Lycium barbarum, Cymbopogon schoenanthus L., Lepidium sativum L. and Marrubium vulgare were six top materia medica identified in this study. Conclusion: Identification of closely related terminology for PCOS in traditional medical texts and prioritization of herbal remedies could be a sound approach to discover new drugs. Accordingly, Ferula assa-foetida L. with the highest score was considered the best candidate for the treatment of PCOS in PM. |
| first_indexed | 2024-04-11T00:08:55Z |
| format | Article |
| id | doaj.art-89e02fa171c74066b1aeda8cbeababa4 |
| institution | Directory Open Access Journal |
| issn | 2717-204X 2717-2058 |
| language | English |
| last_indexed | 2024-04-11T00:08:55Z |
| publishDate | 2022-09-01 |
| publisher | Institue of Medicinal Plants, ACECR |
| record_format | Article |
| series | Journal of Medicinal Plants |
| spelling | doaj.art-89e02fa171c74066b1aeda8cbeababa42023-01-09T08:28:09ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582022-09-012183110Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicineNajmeh Dehparvar0Fatemeh Alijaniha1Seyyed Ali Mozaffarpur2Amir Niasari-Naslaji3Zahra Bahaedin4Ahia Garshasbi5Mohammad Gholami-Fesharak6Mohsen Naseri7 Department of Traditional Persian Medicine, Faculty of Medicine, Shahed University, Tehran, Iran Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran & Department of Traditional Persian Medicine, Faculty of Medicine, Shahed University, Tehran, Iran Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Department of Theriogenology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran & Department of Traditional Persian Medicine, Faculty of Medicine, Shahed University, Tehran, Iran Obstetrics and Gynecology Department, Medical School, Shahed University, Tehran, Iran Department of Biostatistics, Faculty of Medicine, Tarbiat Modares Univesity, Tehran, Iran Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran & Department of Traditional Persian Medicine, Faculty of Medicine, Shahed University, Tehran, Iran Background: According to the reverse pharmacological method, traditional medicine has a good source of information for discovering new drug candidates. Polycystic ovarian syndrome (PCOS) is the most common cause of endocrine disorder and infertility among women of reproductive age. This syndrome is commonly treated by oral contraceptive pills; however, it could be associated with side effects. Objective: The purpose of this study was to identify and prioritize medicinal plants proposed by Persian medicine (PM) for the treatment of PCOS. Methods: The first step was to find out the most relevant keywords to the symptoms of PCOS among five authentic PM manuscripts because there was no medical term called PCOS in PM texts. According to those keywords, all materia medicas that was described in the selected books were recorded. Each materia medica received scores based on specific criteria. The scores were used to prioritize medicaments. Results: Ferula assa-foetida L., Tanacetum parthenium L., Lycium barbarum, Cymbopogon schoenanthus L., Lepidium sativum L. and Marrubium vulgare were six top materia medica identified in this study. Conclusion: Identification of closely related terminology for PCOS in traditional medical texts and prioritization of herbal remedies could be a sound approach to discover new drugs. Accordingly, Ferula assa-foetida L. with the highest score was considered the best candidate for the treatment of PCOS in PM.http://jmp.ir/article-1-3393-en.htmldrug discoverypersian medicinepolycystic ovarian syndromereverse pharmacologytraditional medicine |
| spellingShingle | Najmeh Dehparvar Fatemeh Alijaniha Seyyed Ali Mozaffarpur Amir Niasari-Naslaji Zahra Bahaedin Ahia Garshasbi Mohammad Gholami-Fesharak Mohsen Naseri Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicine Journal of Medicinal Plants drug discovery persian medicine polycystic ovarian syndrome reverse pharmacology traditional medicine |
| title | Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicine |
| title_full | Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicine |
| title_fullStr | Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicine |
| title_full_unstemmed | Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicine |
| title_short | Suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of Persian medicine |
| title_sort | suggested herbal remedies effective on polycystic ovarian syndrome from the viewpoint of persian medicine |
| topic | drug discovery persian medicine polycystic ovarian syndrome reverse pharmacology traditional medicine |
| url | http://jmp.ir/article-1-3393-en.html |
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