A Novel Therapeutic Target for Small-Cell Lung Cancer: Tumor-Associated Repair-like Schwann Cells

A Novel Therapeutic Target for Small-Cell Lung Cancer: Tumor-Associated Repair-like Schwann Cells

Small-cell lung cancer (SCLC), representing 15–20% of all lung cancers, is an aggressive malignancy with a distinct natural history, poor prognosis, and limited treatment options. We have previously identified Schwann cells (SCs), the main glial cells of the peripheral nervous system, in tumor tissu...

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Bibliographic Details
Main Authors: Shuhui Cao, Yue Wang, Yan Zhou, Yao Zhang, Xuxinyi Ling, Lincheng Zhang, Jingwen Li, Yu Yang, Weimin Wang, Michael R. Shurin, Hua Zhong
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
small-cell lung cancer
Schwann cells
tumor progression
miRNA
gene expression
Online Access:https://www.mdpi.com/2072-6694/14/24/6132

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