Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1

Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1

Abstract Background Docosahexaenoic acid (DHA) is a long chain n-3 polyunsaturated fatty acid that has anticancer activity. Heme oxygenase 1 (HO-1) is a potential therapeutic target due to its cytoprotective activity in cancer cells. We recently reported that DHA induces HO-1 gene transcription in h...

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Bibliographic Details
Main Authors: Yang Jiao, Tanya Watts, Jing Xue, Bethany Hannafon, Wei-Qun Ding
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Sorafenib
Docosahexaenoic acid
Cancer
Heme oxygenase 1
Synergy
Online Access:http://link.springer.com/article/10.1186/s12885-018-4946-9

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