Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis

Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis

Cryptococcus neoformans is an opportunistic fungal pathogen preferentially causing disease in immunocompromised individuals such as organ-transplant-recipients, patients receiving immunosuppressive medications or, in particular, individuals suffering from HIV infection. Numerous studies clearly indi...

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Bibliographic Details
Main Authors: Markus Kindermann, Lisa Knipfer, Stephanie Obermeyer, Uwe Müller, Gottfried Alber, Christian Bogdan, Ulrike Schleicher, Markus F. Neurath, Stefan Wirtz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
ILC2
fungi (Candida, Cryptococcus)
innate immunity
lung infection
type 2 immune response
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00209/full

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