Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth

Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth

Dynamic mechanical interactions between adhesion complexes and the cytoskeleton are essential for axon outgrowth and guidance. Whether planar cell polarity (PCP) proteins, which regulate cytoskeleton dynamics and appear necessary for some axon guidance, also mediate interactions with membrane adhesi...

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Bibliographic Details
Main Authors: Steve Dos-Santos Carvalho, Maite M Moreau, Yeri Esther Hien, Mikael Garcia, Nathalie Aubailly, Deborah J Henderson, Vincent Studer, Nathalie Sans, Olivier Thoumine, Mireille Montcouquiol
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
PCP
adhesion
vangl2
cytoskeleton
super-resolution
neuron
Online Access:https://elifesciences.org/articles/51822

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