The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump

In recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable perip...

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Main Authors: Peng Wu, Wenjing Xiang, Chengke Yin, Shu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.766867/full
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author Peng Wu
Wenjing Xiang
Chengke Yin
Shu Li
author_facet Peng Wu
Wenjing Xiang
Chengke Yin
Shu Li
author_sort Peng Wu
collection DOAJ
description In recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable peripheral components, little attention has been paid to the portable and wearable performance of the blood pump itself. This study reported a novel design of a wearable and portable extracorporeal centrifugal blood pump. Based on an in-house centrifugal maglev blood pump, the wearable and portable blood pump was designed with parallel inlet and outlet pipes to improve the wearable performance. A ring cavity was set at the inlet to convert the circumferential velocity of the inlet pipe to an axial velocity. The hydraulic and hemolytic performance of the baseline and portable blood pumps were analyzed and compared. Compared with the baseline pump, the hydrodynamic and hemolytic performance of the portable pump has been maintained without serious degradation. The results of this study will improve the life quality of patients with heart failure, and enhance the clinical benefits of artificial heart.
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spelling doaj.art-89e97405fcf24a21bb344a53d12fa44a2022-12-21T21:48:30ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2021-10-011210.3389/fphys.2021.766867766867The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood PumpPeng Wu0Wenjing Xiang1Chengke Yin2Shu Li3Artificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou, ChinaArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou, ChinaArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou, ChinaInstitute for Medical Device Control, National Institutes for Food and Drug Control, Beijing, ChinaIn recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable peripheral components, little attention has been paid to the portable and wearable performance of the blood pump itself. This study reported a novel design of a wearable and portable extracorporeal centrifugal blood pump. Based on an in-house centrifugal maglev blood pump, the wearable and portable blood pump was designed with parallel inlet and outlet pipes to improve the wearable performance. A ring cavity was set at the inlet to convert the circumferential velocity of the inlet pipe to an axial velocity. The hydraulic and hemolytic performance of the baseline and portable blood pumps were analyzed and compared. Compared with the baseline pump, the hydrodynamic and hemolytic performance of the portable pump has been maintained without serious degradation. The results of this study will improve the life quality of patients with heart failure, and enhance the clinical benefits of artificial heart.https://www.frontiersin.org/articles/10.3389/fphys.2021.766867/fullcentrifugal blood pumpportabilitywearabilityflow fieldCFD
spellingShingle Peng Wu
Wenjing Xiang
Chengke Yin
Shu Li
The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
Frontiers in Physiology
centrifugal blood pump
portability
wearability
flow field
CFD
title The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_full The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_fullStr The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_full_unstemmed The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_short The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_sort design and evaluation of a portable extracorporeal centrifugal blood pump
topic centrifugal blood pump
portability
wearability
flow field
CFD
url https://www.frontiersin.org/articles/10.3389/fphys.2021.766867/full
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