Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 Pandemic
Introduction: The coronavirus (COVID-19) has affected millions of people around the world. COVID-19 patients, particularly those with the critical illness, have coagulation abnormalities, thrombocytopenia, and a high prevalence of intravascular thrombosis. Objectives: This work aims to assess the pr...
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| Format: | Article |
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MDPI AG
2023-03-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/6/1085 |
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| author | Heba Bassiony Ghanem Abozer Y. Elderdery Hana Nassar Alnassar Hadeel Ali Aldandan Wajd Hamed Alkhaldi Kholod Saad Alfuhygy Mjd Muharib Alruwyli Razan Ayed Alayyaf Shoug Khaled Alkhalef Saud Nahar L. Alruwaili Jeremy Mills |
| author_facet | Heba Bassiony Ghanem Abozer Y. Elderdery Hana Nassar Alnassar Hadeel Ali Aldandan Wajd Hamed Alkhaldi Kholod Saad Alfuhygy Mjd Muharib Alruwyli Razan Ayed Alayyaf Shoug Khaled Alkhalef Saud Nahar L. Alruwaili Jeremy Mills |
| author_sort | Heba Bassiony Ghanem |
| collection | DOAJ |
| description | Introduction: The coronavirus (COVID-19) has affected millions of people around the world. COVID-19 patients, particularly those with the critical illness, have coagulation abnormalities, thrombocytopenia, and a high prevalence of intravascular thrombosis. Objectives: This work aims to assess the prevalence of coagulation disorders and their related symptoms among COVID-19 patients in the Al-Jouf region of Saudi Arabia. Subjects and methods: We conducted a retrospective study on 160 COVID-19 patients. Data were collected from the medical records department of King Abdulaziz Specialist Hospital, Sakaka, Al-Jouf, Saudi Arabia. The socio-demographic data, risk factors, coagulation profile investigation results, symptom and sign data related to coagulation disorders, and disease morbidity and mortality for COVID-19 patients were extracted from medical records, and the data were stored confidentially. Results: Males represented the highest prevalence of COVID-19 infection at 65%; 29% were aged 60 or over; 28% were smokers; and 36% were suffering from chronic diseases, with diabetes mellitus representing the highest prevalence. Positive D-dimer results occurred in 29% of cases, with abnormal platelet counts in 26%. Conclusion: Our findings confirm that the dysregulation of the coagulation cascade and the subsequent occurrence of coagulation disorders are common in coronavirus infections. The results show absolute values, not increases over normal values; thus, it is hard to justify increased risk and presence based on the presented data. |
| first_indexed | 2024-03-11T06:41:57Z |
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| id | doaj.art-89ebc4a75c6e411aa1e3e016bec88790 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T06:41:57Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-89ebc4a75c6e411aa1e3e016bec887902023-11-17T10:34:08ZengMDPI AGDiagnostics2075-44182023-03-01136108510.3390/diagnostics13061085Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 PandemicHeba Bassiony Ghanem0Abozer Y. Elderdery1Hana Nassar Alnassar2Hadeel Ali Aldandan3Wajd Hamed Alkhaldi4Kholod Saad Alfuhygy5Mjd Muharib Alruwyli6Razan Ayed Alayyaf7Shoug Khaled Alkhalef8Saud Nahar L. Alruwaili9Jeremy Mills10Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi ArabiaRegional Laboratory, Ministry of Health, Al-Jouf, Sakaka 72345, Saudi ArabiaSchool of Pharmacy and Biomedical Sciences, Portsmouth PO1 2DT, UKIntroduction: The coronavirus (COVID-19) has affected millions of people around the world. COVID-19 patients, particularly those with the critical illness, have coagulation abnormalities, thrombocytopenia, and a high prevalence of intravascular thrombosis. Objectives: This work aims to assess the prevalence of coagulation disorders and their related symptoms among COVID-19 patients in the Al-Jouf region of Saudi Arabia. Subjects and methods: We conducted a retrospective study on 160 COVID-19 patients. Data were collected from the medical records department of King Abdulaziz Specialist Hospital, Sakaka, Al-Jouf, Saudi Arabia. The socio-demographic data, risk factors, coagulation profile investigation results, symptom and sign data related to coagulation disorders, and disease morbidity and mortality for COVID-19 patients were extracted from medical records, and the data were stored confidentially. Results: Males represented the highest prevalence of COVID-19 infection at 65%; 29% were aged 60 or over; 28% were smokers; and 36% were suffering from chronic diseases, with diabetes mellitus representing the highest prevalence. Positive D-dimer results occurred in 29% of cases, with abnormal platelet counts in 26%. Conclusion: Our findings confirm that the dysregulation of the coagulation cascade and the subsequent occurrence of coagulation disorders are common in coronavirus infections. The results show absolute values, not increases over normal values; thus, it is hard to justify increased risk and presence based on the presented data.https://www.mdpi.com/2075-4418/13/6/1085COVID-19coagulation disordersD-dimerSARS-CoV-2symptoms |
| spellingShingle | Heba Bassiony Ghanem Abozer Y. Elderdery Hana Nassar Alnassar Hadeel Ali Aldandan Wajd Hamed Alkhaldi Kholod Saad Alfuhygy Mjd Muharib Alruwyli Razan Ayed Alayyaf Shoug Khaled Alkhalef Saud Nahar L. Alruwaili Jeremy Mills Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 Pandemic Diagnostics COVID-19 coagulation disorders D-dimer SARS-CoV-2 symptoms |
| title | Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 Pandemic |
| title_full | Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 Pandemic |
| title_fullStr | Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 Pandemic |
| title_full_unstemmed | Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 Pandemic |
| title_short | Study of Coagulation Disorders and the Prevalence of Their Related Symptoms among COVID-19 Patients in Al-Jouf Region, Saudi Arabia during the COVID-19 Pandemic |
| title_sort | study of coagulation disorders and the prevalence of their related symptoms among covid 19 patients in al jouf region saudi arabia during the covid 19 pandemic |
| topic | COVID-19 coagulation disorders D-dimer SARS-CoV-2 symptoms |
| url | https://www.mdpi.com/2075-4418/13/6/1085 |
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