Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient
We report a hemodialysis MDR HIV-infected patient switched to fostemsavir with lenacapavir plus lamivudine for more than a year. She maintained a suppressed viral replication and did not present any clinical or biological drug-related side effects. The combination of lenacapavir plus fostemsavir loo...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2023-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2023/8865265 |
| _version_ | 1797649719074226176 |
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| author | Ferdinand Bigirimana Sigi Van den Wijngaert Christelle Fosso Karolien Stoffels Charlotte Martin Evelyne Maillart Philippe Clevenbergh |
| author_facet | Ferdinand Bigirimana Sigi Van den Wijngaert Christelle Fosso Karolien Stoffels Charlotte Martin Evelyne Maillart Philippe Clevenbergh |
| author_sort | Ferdinand Bigirimana |
| collection | DOAJ |
| description | We report a hemodialysis MDR HIV-infected patient switched to fostemsavir with lenacapavir plus lamivudine for more than a year. She maintained a suppressed viral replication and did not present any clinical or biological drug-related side effects. The combination of lenacapavir plus fostemsavir looks promising in terms of safety and efficacy even in patients with end-stage renal disease awaiting renal transplant. Both drugs are first in class ARVs so that there is no cross resistance with previous drugs, maintaining their efficacy against MDR HIV. |
| first_indexed | 2024-03-11T15:51:04Z |
| format | Article |
| id | doaj.art-89ee7c1e1ef148b2be34e82cb89c0539 |
| institution | Directory Open Access Journal |
| issn | 2090-6633 |
| language | English |
| last_indexed | 2024-03-11T15:51:04Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj.art-89ee7c1e1ef148b2be34e82cb89c05392023-10-26T00:00:01ZengHindawi LimitedCase Reports in Infectious Diseases2090-66332023-01-01202310.1155/2023/8865265Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis PatientFerdinand Bigirimana0Sigi Van den Wijngaert1Christelle Fosso2Karolien Stoffels3Charlotte Martin4Evelyne Maillart5Philippe Clevenbergh6Infectious Diseases DepartmentAids Reference LaboratoryNephrology and Dialysis DepartmentAids Reference LaboratoryInfectious Diseases DepartmentInfectious Diseases DepartmentInfectious Diseases DepartmentWe report a hemodialysis MDR HIV-infected patient switched to fostemsavir with lenacapavir plus lamivudine for more than a year. She maintained a suppressed viral replication and did not present any clinical or biological drug-related side effects. The combination of lenacapavir plus fostemsavir looks promising in terms of safety and efficacy even in patients with end-stage renal disease awaiting renal transplant. Both drugs are first in class ARVs so that there is no cross resistance with previous drugs, maintaining their efficacy against MDR HIV.http://dx.doi.org/10.1155/2023/8865265 |
| spellingShingle | Ferdinand Bigirimana Sigi Van den Wijngaert Christelle Fosso Karolien Stoffels Charlotte Martin Evelyne Maillart Philippe Clevenbergh Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient Case Reports in Infectious Diseases |
| title | Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient |
| title_full | Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient |
| title_fullStr | Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient |
| title_full_unstemmed | Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient |
| title_short | Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient |
| title_sort | lenacapavir with fostemsavir in a multidrug resistant hiv infected hemodialysis patient |
| url | http://dx.doi.org/10.1155/2023/8865265 |
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