ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation

Objective: Insulin suppresses adipose tissue lipolysis after a meal, playing a key role in metabolic homeostasis. This is mediated via the kinase Akt and its substrate phosphodiesterase 3B (PDE3B). Once phosphorylated and activated, PDE3B hydrolyses cAMP leading to the inactivation of cAMP-dependent...

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Bibliographic Details
Main Authors:	Jacqueline Stöckli, Armella Zadoorian, Kristen C. Cooke, Vinita Deshpande, Belinda Yau, Gaia Herrmann, Melkam A. Kebede, Sean J. Humphrey, David E. James
Format:	Article
Language:	English
Published:	Elsevier 2019-07-01
Series:	Molecular Metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877819303278

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