A case of bony lytic lesions in a patient with Gaucher disease
Abstract Gaucher disease is a clinically heterogeneous disorder of glucocerebroside metabolism and may present incidentally late in life with unexplained thrombocytopenia, splenomegaly, or bony lesions. Clinicians should be aware that patients with Gaucher disease appear to have an increased risk fo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-09-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.2329 |
| _version_ | 1818887238977585152 |
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| author | Eric McGinnis Habib Moshref Razavi |
| author_facet | Eric McGinnis Habib Moshref Razavi |
| author_sort | Eric McGinnis |
| collection | DOAJ |
| description | Abstract Gaucher disease is a clinically heterogeneous disorder of glucocerebroside metabolism and may present incidentally late in life with unexplained thrombocytopenia, splenomegaly, or bony lesions. Clinicians should be aware that patients with Gaucher disease appear to have an increased risk for developing hematolymphoid malignancies, particularly monoclonal gammopathies and plasma cell myeloma. |
| first_indexed | 2024-12-19T16:34:04Z |
| format | Article |
| id | doaj.art-89f407cf41ca41bfac4b3fe23f25bb66 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-12-19T16:34:04Z |
| publishDate | 2019-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-89f407cf41ca41bfac4b3fe23f25bb662022-12-21T20:14:01ZengWileyClinical Case Reports2050-09042019-09-01791685168810.1002/ccr3.2329A case of bony lytic lesions in a patient with Gaucher diseaseEric McGinnis0Habib Moshref Razavi1Division of Hematopathology, Department of Pathology and Laboratory Medicine University of British Columbia Vancouver British Columbia CanadaFraser Health Authority Royal Columbian Hospital New Westminster British Columbia CanadaAbstract Gaucher disease is a clinically heterogeneous disorder of glucocerebroside metabolism and may present incidentally late in life with unexplained thrombocytopenia, splenomegaly, or bony lesions. Clinicians should be aware that patients with Gaucher disease appear to have an increased risk for developing hematolymphoid malignancies, particularly monoclonal gammopathies and plasma cell myeloma.https://doi.org/10.1002/ccr3.2329diagnostic immunohistochemistryGaucher diseaseplasma cell myeloma |
| spellingShingle | Eric McGinnis Habib Moshref Razavi A case of bony lytic lesions in a patient with Gaucher disease Clinical Case Reports diagnostic immunohistochemistry Gaucher disease plasma cell myeloma |
| title | A case of bony lytic lesions in a patient with Gaucher disease |
| title_full | A case of bony lytic lesions in a patient with Gaucher disease |
| title_fullStr | A case of bony lytic lesions in a patient with Gaucher disease |
| title_full_unstemmed | A case of bony lytic lesions in a patient with Gaucher disease |
| title_short | A case of bony lytic lesions in a patient with Gaucher disease |
| title_sort | case of bony lytic lesions in a patient with gaucher disease |
| topic | diagnostic immunohistochemistry Gaucher disease plasma cell myeloma |
| url | https://doi.org/10.1002/ccr3.2329 |
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