Engineering the Bridge between Innate and Adaptive Immunity for Cancer Immunotherapy: Focus on γδ T and NK Cells

Engineering the Bridge between Innate and Adaptive Immunity for Cancer Immunotherapy: Focus on γδ T and NK Cells

Most studies on genetic engineering technologies for cancer immunotherapy based on allogeneic donors have focused on adaptive immunity. However, the main limitation of such approaches is that they can lead to severe graft-versus-host disease (GvHD). An alternative approach would bolster innate immun...

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Bibliographic Details
Main Authors: Fabio Morandi, Mahboubeh Yazdanifar, Claudia Cocco, Alice Bertaina, Irma Airoldi
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
gamma delta T cells
NK cells
γδT cells
immunotherapy
adoptive cell therapy
GvHD
Online Access:https://www.mdpi.com/2073-4409/9/8/1757

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