Organisation of the orthobunyavirus tripodal spike and the structural changes induced by low pH and K+ during entry
Abstract Following endocytosis, enveloped viruses employ the changing environment of maturing endosomes as cues to promote endosomal escape, a process often mediated by viral glycoproteins. We previously showed that both high [K+] and low pH promote entry of Bunyamwera virus (BUNV), the prototypical...
Main Authors: | Samantha Hover, Frank W. Charlton, Jan Hellert, Jessica J. Swanson, Jamel Mankouri, John N. Barr, Juan Fontana |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-41205-w |
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