Collective cell mechanics of epithelial shells with organoid-like morphologies
The physical origins of man-made tissue morphologies with organ-like microscopic anatomy and functionality remain poorly understood. Here, authors propose a mechanistic theory of these structures, employing a 3D vertex model to reproduce the characteristic morphologies such as branched shapes.
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-07-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-17535-4 |
_version_ | 1819200353038499840 |
---|---|
author | Jan Rozman Matej Krajnc Primož Ziherl |
author_facet | Jan Rozman Matej Krajnc Primož Ziherl |
author_sort | Jan Rozman |
collection | DOAJ |
description | The physical origins of man-made tissue morphologies with organ-like microscopic anatomy and functionality remain poorly understood. Here, authors propose a mechanistic theory of these structures, employing a 3D vertex model to reproduce the characteristic morphologies such as branched shapes. |
first_indexed | 2024-12-23T03:30:53Z |
format | Article |
id | doaj.art-89f72efd68ce42ac98995d4580317551 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-23T03:30:53Z |
publishDate | 2020-07-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-89f72efd68ce42ac98995d45803175512022-12-21T18:01:42ZengNature PortfolioNature Communications2041-17232020-07-011111910.1038/s41467-020-17535-4Collective cell mechanics of epithelial shells with organoid-like morphologiesJan Rozman0Matej Krajnc1Primož Ziherl2Jožef Stefan InstituteJožef Stefan InstituteJožef Stefan InstituteThe physical origins of man-made tissue morphologies with organ-like microscopic anatomy and functionality remain poorly understood. Here, authors propose a mechanistic theory of these structures, employing a 3D vertex model to reproduce the characteristic morphologies such as branched shapes.https://doi.org/10.1038/s41467-020-17535-4 |
spellingShingle | Jan Rozman Matej Krajnc Primož Ziherl Collective cell mechanics of epithelial shells with organoid-like morphologies Nature Communications |
title | Collective cell mechanics of epithelial shells with organoid-like morphologies |
title_full | Collective cell mechanics of epithelial shells with organoid-like morphologies |
title_fullStr | Collective cell mechanics of epithelial shells with organoid-like morphologies |
title_full_unstemmed | Collective cell mechanics of epithelial shells with organoid-like morphologies |
title_short | Collective cell mechanics of epithelial shells with organoid-like morphologies |
title_sort | collective cell mechanics of epithelial shells with organoid like morphologies |
url | https://doi.org/10.1038/s41467-020-17535-4 |
work_keys_str_mv | AT janrozman collectivecellmechanicsofepithelialshellswithorganoidlikemorphologies AT matejkrajnc collectivecellmechanicsofepithelialshellswithorganoidlikemorphologies AT primozziherl collectivecellmechanicsofepithelialshellswithorganoidlikemorphologies |