Bone-Marrow-Derived Mesenchymal Stem Cells Attenuate Behavioral and Cognitive Dysfunction after Subarachnoid Hemorrhage via HMGB1–RAGE Axis Mediation

Bone-Marrow-Derived Mesenchymal Stem Cells Attenuate Behavioral and Cognitive Dysfunction after Subarachnoid Hemorrhage via HMGB1–RAGE Axis Mediation

We evaluated the therapeutic effects of bone-marrow-derived mesenchymal stem cells (BMSCs) on behavioral and cognitive function in a mouse model of mild subarachnoid hemorrhage (SAH) and explored the underlying mechanisms in conjunction with the HMGB1–RAGE axis. The SAH models were generated in a to...

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Bibliographic Details
Main Authors: Harry Jung, Dong Hyuk Youn, Jeong Jin Park, Jin Pyeong Jeon
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Life
Subjects:
subarachnoid hemorrhage
bone-marrow mesenchymal stem cells
cognitive impairment
high-mobility group box 1
Online Access:https://www.mdpi.com/2075-1729/13/4/881

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