An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma
A case of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome, which develops in the course of ACTH-dependent Cushing’s disease, is presented in this report. A 47-year-old woman with a past history of surgery and gamma knife radiosurgery because of Cushing’s disease was admitted to the...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2017-03-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: | http://www.hasekidergisi.com/article_14826/An-Unusual-Case-Of-Cushings-Syndrome-Coexistence-Of-Functional-Pituitary-And-Adrenal-Adenoma |
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| author | Muzaffer İlhan Özcan Karaman İrem Yasin Çetin Nur Büyükpınarbaşılı Jamshid Hamdard Ertuğrul Taşan |
| author_facet | Muzaffer İlhan Özcan Karaman İrem Yasin Çetin Nur Büyükpınarbaşılı Jamshid Hamdard Ertuğrul Taşan |
| author_sort | Muzaffer İlhan |
| collection | DOAJ |
| description | A case of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome, which develops in the course of ACTH-dependent Cushing’s disease, is presented in this report. A 47-year-old woman with a past history of surgery and gamma knife radiosurgery because of Cushing’s disease was admitted to the endocrinology clinic with weight gain and unregulated blood glucose levels. Hypercortisolemia was still persisting and diagnostic work-up indicated ACTH-independent Cushing’s syndrome. Along with the rare possibility of this coexistence, longstanding ACTH hypersecretion can play a role in functional transition of adrenal adenomas. Further studies are needed to clarify the underlying mechanisms. |
| first_indexed | 2024-04-10T14:30:43Z |
| format | Article |
| id | doaj.art-8a00f45638e0489c82f79ea69ecedabf |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T14:30:43Z |
| publishDate | 2017-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-8a00f45638e0489c82f79ea69ecedabf2023-02-15T16:08:50ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882017-03-01551616310.4274/haseki.3073An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal AdenomaMuzaffer İlhan0Özcan Karaman1İrem Yasin Çetin2Nur Büyükpınarbaşılı3Jamshid Hamdard4Ertuğrul Taşan5Ümraniye Training and Research Hospital, Clinic of Endocrinology and Metabolism Diseases, İstanbul, TurkeyBezmialem Vakıf University Faculty of Medicine, Department of Endocrinology and Metabolism Diseases, İstanbul, TurkeyBezmialem Vakıf University Faculty of Medicine, Department of Internal Diseases, İstanbul, TurkeyBezmialem Vakıf University Faculty of Medicine, Department of Pathology, İstanbul, TurkeyBezmialem Vakıf University Faculty of Medicine, Department of Internal Diseases, İstanbul, TurkeyBezmialem Vakıf University Faculty of Medicine, Department of Endocrinology and Metabolism Diseases, İstanbul, TurkeyA case of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome, which develops in the course of ACTH-dependent Cushing’s disease, is presented in this report. A 47-year-old woman with a past history of surgery and gamma knife radiosurgery because of Cushing’s disease was admitted to the endocrinology clinic with weight gain and unregulated blood glucose levels. Hypercortisolemia was still persisting and diagnostic work-up indicated ACTH-independent Cushing’s syndrome. Along with the rare possibility of this coexistence, longstanding ACTH hypersecretion can play a role in functional transition of adrenal adenomas. Further studies are needed to clarify the underlying mechanisms.http://www.hasekidergisi.com/article_14826/An-Unusual-Case-Of-Cushings-Syndrome-Coexistence-Of-Functional-Pituitary-And-Adrenal-AdenomaCushing’s syndromeCushing’s diseaseadrenal adenoma |
| spellingShingle | Muzaffer İlhan Özcan Karaman İrem Yasin Çetin Nur Büyükpınarbaşılı Jamshid Hamdard Ertuğrul Taşan An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma Haseki Tıp Bülteni Cushing’s syndrome Cushing’s disease adrenal adenoma |
| title | An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma |
| title_full | An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma |
| title_fullStr | An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma |
| title_full_unstemmed | An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma |
| title_short | An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma |
| title_sort | unusual case of cushing s syndrome coexistence of functional pituitary and adrenal adenoma |
| topic | Cushing’s syndrome Cushing’s disease adrenal adenoma |
| url | http://www.hasekidergisi.com/article_14826/An-Unusual-Case-Of-Cushings-Syndrome-Coexistence-Of-Functional-Pituitary-And-Adrenal-Adenoma |
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