Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS

Dihydrotanshinone I preconditions myocardium against ischemic injury via PKM2 glutathionylation sensitive to ROS

Ischemic preconditioning (IPC) is a potential intervention known to protect the heart against ischemia/reperfusion injury, but its role in the no-reflow phenomenon that follows reperfusion is unclear. Dihydrotanshinone I (DT) is a natural compound and this study illustrates its role in cardiac ische...

Full description

Bibliographic Details
Main Authors: Xunxun Wu, Lian Liu, Qiuling Zheng, Hui Ye, Hua Yang, Haiping Hao, Ping Li
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Dihydrotanshinone I
Ischemic preconditioning
PKM2
Glutathionylation
Myocardial ischemia
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522003185

Similar Items

Similar Items