Optic neuritis in a child with biotinidase deficiency case report and literature review
Abdul-Aziz Hayati1, Wan-Hazabbah Wan-Hitam1, Min-Tet Cheong1, Rohaizan Yunus2, Ismail Shatriah11Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia; 2Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2012-03-01
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| Series: | Clinical Ophthalmology |
| Online Access: | http://www.dovepress.com/optic-neuritis-in-a-child-with-biotinidase-deficiency-case-report-and--a9477 |
| _version_ | 1831519612300165120 |
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| author | Hayati AA Wan-Hitam WH Cheong MT Yunus R Shatriah I |
| author_facet | Hayati AA Wan-Hitam WH Cheong MT Yunus R Shatriah I |
| author_sort | Hayati AA |
| collection | DOAJ |
| description | Abdul-Aziz Hayati1, Wan-Hazabbah Wan-Hitam1, Min-Tet Cheong1, Rohaizan Yunus2, Ismail Shatriah11Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia; 2Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, MalaysiaAbstract: Optic atrophy has often been reported in children with biotinidase deficiency. The visual prognosis is usually poor. This report is of a 6-year-old boy with an early onset of biotinidase deficiency who presented with acute profound visual loss in both eyes. Fundoscopy revealed swollen discs in both eyes, and the imaging was consistent with bilateral optic neuritis. He was treated with systemic corticosteroid, and commenced on oral biotin. The final visual outcome was promising.Keywords: optic neuritis, children, biotinidase deficiency |
| first_indexed | 2024-12-13T17:17:06Z |
| format | Article |
| id | doaj.art-8a0813d3bd3046439fc64b96e6d85fec |
| institution | Directory Open Access Journal |
| issn | 1177-5467 1177-5483 |
| language | English |
| last_indexed | 2024-12-13T17:17:06Z |
| publishDate | 2012-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-8a0813d3bd3046439fc64b96e6d85fec2022-12-21T23:37:24ZengDove Medical PressClinical Ophthalmology1177-54671177-54832012-03-012012default389395Optic neuritis in a child with biotinidase deficiency case report and literature reviewHayati AAWan-Hitam WHCheong MTYunus RShatriah IAbdul-Aziz Hayati1, Wan-Hazabbah Wan-Hitam1, Min-Tet Cheong1, Rohaizan Yunus2, Ismail Shatriah11Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia; 2Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, MalaysiaAbstract: Optic atrophy has often been reported in children with biotinidase deficiency. The visual prognosis is usually poor. This report is of a 6-year-old boy with an early onset of biotinidase deficiency who presented with acute profound visual loss in both eyes. Fundoscopy revealed swollen discs in both eyes, and the imaging was consistent with bilateral optic neuritis. He was treated with systemic corticosteroid, and commenced on oral biotin. The final visual outcome was promising.Keywords: optic neuritis, children, biotinidase deficiencyhttp://www.dovepress.com/optic-neuritis-in-a-child-with-biotinidase-deficiency-case-report-and--a9477 |
| spellingShingle | Hayati AA Wan-Hitam WH Cheong MT Yunus R Shatriah I Optic neuritis in a child with biotinidase deficiency case report and literature review Clinical Ophthalmology |
| title | Optic neuritis in a child with biotinidase deficiency case report and literature review |
| title_full | Optic neuritis in a child with biotinidase deficiency case report and literature review |
| title_fullStr | Optic neuritis in a child with biotinidase deficiency case report and literature review |
| title_full_unstemmed | Optic neuritis in a child with biotinidase deficiency case report and literature review |
| title_short | Optic neuritis in a child with biotinidase deficiency case report and literature review |
| title_sort | optic neuritis in a child with biotinidase deficiency case report and literature review |
| url | http://www.dovepress.com/optic-neuritis-in-a-child-with-biotinidase-deficiency-case-report-and--a9477 |
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