The Effect of a 13-Valent Conjugate Pneumococcal Vaccine on Circulating Antibodies Against Oxidized LDL and Phosphorylcholine in Man, A Randomized Placebo-Controlled Clinical Trial

The Effect of a 13-Valent Conjugate Pneumococcal Vaccine on Circulating Antibodies Against Oxidized LDL and Phosphorylcholine in Man, A Randomized Placebo-Controlled Clinical Trial

In mice vaccination with <i>Streptococcus pneumoniae</i> results in an increase in anti-oxLDL IgM antibodies due to mimicry of anti-phosphorylcholine (present in the cell wall of <i>S. pneumoniae</i>) and anti-oxLDL IgM. In this study we investigated the human translation of...

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Bibliographic Details
Main Authors: Hendrika W. Grievink, Pim Gal, Maria Ozsvar Kozma, Erica S. Klaassen, Johan Kuiper, Jacobus Burggraaf, Christoph J. Binder, Matthijs Moerland
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biology
Subjects:
cardiovascular disease
vaccine
clinical trials
translational medicine
atherosclerosis
oxLDL
Online Access:https://www.mdpi.com/2079-7737/9/11/345

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