Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer

Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer

Introduction: Gastric cancer (GC)is the third leading cause of cancer-related deaths in China and immunotherapy emerging as a revolutionary treatment for GC recently. Tumor mutational burden (TMB) is a predictive biomarker of immunotherapy in multiple cancers. However, the prognostic significance an...

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Bibliographic Details
Main Authors:	Yanan Cheng, Dechao Bu, Qiaoling Zhang, Rebecca Sun, Stephen Lyle, Gang Zhao, Li Dong, Hui Li, Yi Zhao, Jinpu Yu, Xishan Hao
Format:	Article
Language:	English
Published:	Elsevier 2023-09-01
Series:	Journal of Advanced Research
Subjects:	Gastric cancer Comprehensive genomic profiling TMB Mutational signature Tumor metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S209012322200248X

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