The Therapeutic Efficacy and Mechanism of Action of Gnetin C, a Natural Compound from the Melinjo Plant, in a Preclinical Mouse Model of Advanced Prostate Cancer

The Therapeutic Efficacy and Mechanism of Action of Gnetin C, a Natural Compound from the Melinjo Plant, in a Preclinical Mouse Model of Advanced Prostate Cancer

The metastasis-associated protein 1/protein kinase B (MTA1/AKT) signaling pathway has been shown to cooperate in promoting prostate tumor growth. Targeted interception strategies by plant-based polyphenols, specifically stilbenes, have shown great promise against MTA1-mediated prostate cancer progre...

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Bibliographic Details
Main Authors: Gisella Campanelli, Ekniel Francois, Prashanth Parupathi, Lakshmi Sirisha Devarakonda, Ching Yang, Avinash Kumar, Anait S. Levenson
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cancers
Subjects:
natural products
plant-derived polyphenols
gnetin C
targeted therapeutics
anticancer effects
MTA1/mTOR
Online Access:https://www.mdpi.com/2072-6694/16/7/1344

Internet

https://www.mdpi.com/2072-6694/16/7/1344

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