Underestimation of the Maximal Capacity of the Mitochondrial Electron Transport System in Oligomycin-Treated Cells.

The maximal capacity of the mitochondrial electron transport system (ETS) in intact cells is frequently estimated by promoting protonophore-induced maximal oxygen consumption preceded by inhibition of oxidative phosphorylation by oligomycin. In the present study, human glioma (T98G and U-87MG) and p...

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Bibliographic Details
Main Authors: Juliana S Ruas, Edilene S Siqueira-Santos, Ignacio Amigo, Erika Rodrigues-Silva, Alicia J Kowaltowski, Roger F Castilho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4780810?pdf=render